[HTML][HTML] Physiology and pathophysiology of carnosine

AA Boldyrev, G Aldini, W Derave - Physiological reviews, 2013 - journals.physiology.org
Abstract Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-
protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal …

Carnosine as an effective neuroprotector in brain pathology and potential neuromodulator in normal conditions

DS Berezhnoy, SL Stvolinsky, AV Lopachev… - Amino acids, 2019 - Springer
Abstract Carnosine (b-alanyl-l-histidine) is an endogenous dipeptide widely distributed in
excitable tissues, such as muscle and neural tissues—though in minor concentrations in the …

Carnosine and its possible roles in nutrition and health

AR Hipkiss - Advances in food and nutrition research, 2009 - Elsevier
The dipeptide carnosine has been observed to exert antiaging activity at cellular and whole
animal levels. This review discusses the possible mechanisms by which carnosine may …

[HTML][HTML] Carnosine, small but mighty—prospect of use as functional ingredient for functional food formulation

I Jukić, N Kolobarić, A Stupin, A Matić, N Kozina… - Antioxidants, 2021 - mdpi.com
Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found
in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is …

Pivotal role of carnosine in the modulation of brain cells activity: Multimodal mechanism of action and therapeutic potential in neurodegenerative disorders

G Caruso, F Caraci, RB Jolivet - Progress in neurobiology, 2019 - Elsevier
Abstract Carnosine (β-alanyl-l-histidine), a dipeptide, is an endogenous antioxidant widely
distributed in excitable tissues like muscles and the brain. Although discovered more than a …

Neuroprotective features of carnosine in oxidative driven diseases

F Bellia, G Vecchio, S Cuzzocrea, V Calabrese… - Molecular aspects of …, 2011 - Elsevier
Carnosine (β-alanyl-l-histidine) is a natural dipeptide widely and abundantly distributed in
excitable tissues of several animal tissues. Although its physiological role has not been …

Carnosine: from exercise performance to health

C Sale, GG Artioli, B Gualano, B Saunders, RM Hobson… - Amino acids, 2013 - Springer
Carnosine was first discovered in skeletal muscle, where its concentration is higher than in
any other tissue. This, along with an understanding of its role as an intracellular pH buffer …

Physiological and therapeutic effects of carnosine on cardiometabolic risk and disease

E Baye, B Ukropcova, J Ukropec, A Hipkiss, G Aldini… - Amino acids, 2016 - Springer
Abstract Obesity, type 2 diabetes (T2DM) and cardiovascular disease (CVD) are the most
common preventable causes of morbidity and mortality worldwide. They represent major …

Carnosine: its properties, functions and potential therapeutic applications

PJ Quinn, AA Boldyrev, VE Formazuyk - Molecular aspects of Medicine, 1992 - Elsevier
Carnosine and related dipeptides such as anserine are naturally-occurring histidine-
containing compounds. They are found in several tissues most notably in muscle where they …

[HTML][HTML] Carnosine and beta-alanine supplementation in human medicine: narrative review and critical assessment

O Cesak, J Vostalova, A Vidlar, P Bastlova… - Nutrients, 2023 - mdpi.com
The dipeptide carnosine is a physiologically important molecule in the human body,
commonly found in skeletal muscle and brain tissue. Beta-alanine is a limiting precursor of …