Alternative splicing is the molecular process that generates multiple mRNA variants from
single eukaryotic genes through variable assortment of their exons (1, 2). This process …

Pre-mRNA splicing, an essential step in eukaryotic gene expression, relies on recognition of
short sequences on the primary transcript intron ends and takes place along transcription by …

Alternative splicing is a key process of post-transcriptional gene regulation that provides
transcriptome and proteome diversity by allowing the production of various RNA isoforms …

Alternative splicing (AS) allows a messenger RNA (mRNA) to control the production of
various protein variations (isoforms) with distinct biological activities. It involves altering the …

Alternative splicing (AS), a crucial cellular process, is a source of transcriptomic expansion
and protein variability. Its contribution to cancer development and progression among a vast …

Recent advances in high‐throughput sequencing technologies have unexpectedly revealed
that somatic mutations of splicing factor genes frequently occurred in several types of …

Alternative splicing is a key molecular event in the gene expression process. It allows for the
synthesis of different products from the same gene, and consequently increases the …

Dysregulated RNA splicing is a hallmark feature of cancer. Much like mutational signatures
in tumors, RNA mis-splicing patterns are widely heterogeneous and segregate tumors into …

The discovery of an increasing number of alternative splicing events in the human genome
highlighted that∼ 94% of genes generate alternatively spliced transcripts that may produce …

Alternative splicing is a tightly regulated process whereby non-coding sequences of pre-
mRNA are removed and protein-coding segments are assembled in diverse combinations …