[图书][B] Women in cancer genetics vol II: 2022
GT Torrezan, P Mehdipour - 2023 - books.google.com
Alternative splicing is the molecular process that generates multiple mRNA variants from
single eukaryotic genes through variable assortment of their exons (1, 2). This process …
single eukaryotic genes through variable assortment of their exons (1, 2). This process …
Understanding human DNA variants affecting pre-mRNA splicing in the NGS era
LG Dufner-Almeida, RT do Carmo, C Masotti… - Advances in …, 2019 - Elsevier
Pre-mRNA splicing, an essential step in eukaryotic gene expression, relies on recognition of
short sequences on the primary transcript intron ends and takes place along transcription by …
short sequences on the primary transcript intron ends and takes place along transcription by …
Alternative Splicing and Cancer
Alternative splicing is a key process of post-transcriptional gene regulation that provides
transcriptome and proteome diversity by allowing the production of various RNA isoforms …
transcriptome and proteome diversity by allowing the production of various RNA isoforms …
Alternative Splicing and Human Diseases
M Tanwar - Alternative Splicing and Cancer - taylorfrancis.com
Alternative splicing (AS) allows a messenger RNA (mRNA) to control the production of
various protein variations (isoforms) with distinct biological activities. It involves altering the …
various protein variations (isoforms) with distinct biological activities. It involves altering the …
Reclassification of Splicing Gene Variants in Hereditary Cancer: Cases Report and Literature Review
D Bouzarelou, K Agiannitopoulos, GN Tsaousis… - in vivo, 2023 - iv.iiarjournals.org
Alternative splicing (AS), a crucial cellular process, is a source of transcriptomic expansion
and protein variability. Its contribution to cancer development and progression among a vast …
and protein variability. Its contribution to cancer development and progression among a vast …
Splicing factor mutations and cancer
Recent advances in high‐throughput sequencing technologies have unexpectedly revealed
that somatic mutations of splicing factor genes frequently occurred in several types of …
that somatic mutations of splicing factor genes frequently occurred in several types of …
Alternative splicing and breast cancer
M Dutertre, S Vagner, D Auboeuf - RNA biology, 2010 - Taylor & Francis
Alternative splicing is a key molecular event in the gene expression process. It allows for the
synthesis of different products from the same gene, and consequently increases the …
synthesis of different products from the same gene, and consequently increases the …
Abstract IA022: Mechanisms of splicing dysregulation and dependency in cancer
K Karlin - Molecular Cancer Therapeutics, 2024 - AACR
Dysregulated RNA splicing is a hallmark feature of cancer. Much like mutational signatures
in tumors, RNA mis-splicing patterns are widely heterogeneous and segregate tumors into …
in tumors, RNA mis-splicing patterns are widely heterogeneous and segregate tumors into …
A saga of cancer epigenetics: linking epigenetics to alternative splicing
The discovery of an increasing number of alternative splicing events in the human genome
highlighted that∼ 94% of genes generate alternatively spliced transcripts that may produce …
highlighted that∼ 94% of genes generate alternatively spliced transcripts that may produce …
[HTML][HTML] The role of alternative splicing in cancer: From oncogenesis to drug resistance
R Sciarrillo, A Wojtuszkiewicz, YG Assaraf… - Drug Resistance …, 2020 - Elsevier
Alternative splicing is a tightly regulated process whereby non-coding sequences of pre-
mRNA are removed and protein-coding segments are assembled in diverse combinations …
mRNA are removed and protein-coding segments are assembled in diverse combinations …