Automated comparative protein structure modeling with SWISS‐MODEL and Swiss‐PdbViewer: A historical perspective

N Guex, MC Peitsch, T Schwede - Electrophoresis, 2009 - Wiley Online Library
SWISS‐MODEL pioneered the field of automated modeling as the first protein modeling
service on the Internet. In combination with the visualization tool Swiss‐PdbViewer, the …

SWISS‐MODEL and the Swiss‐Pdb Viewer: an environment for comparative protein modeling

N Guex, MC Peitsch - electrophoresis, 1997 - Wiley Online Library
Comparative protein modeling is increasingly gaining interest since it is of great assistance
during the rational design of mutagenesis experiments. The availability of this method, and …

[HTML][HTML] Protein structure computing in the genomic era

T Schwede, A Diemand, N Guex, MC Peitsch - Research in Microbiology, 2000 - Elsevier
Functional analysis of the proteins discovered in fully sequenced genomes represents the
next major challenge of life science research. Computational methods play a crucial role in …

Automated protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal

L Bordoli, T Schwede - Homology Modeling: Methods and Protocols, 2012 - Springer
Comparative protein structure modeling is a computational approach to build three-
dimensional structural models for proteins using experimental structures of related protein …

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

K Arnold, L Bordoli, J Kopp, T Schwede - Bioinformatics, 2006 - academic.oup.com
Motivation: Homology models of proteins are of great interest for planning and analysing
biological experiments when no experimental three-dimensional structures are available …

Protein structure modeling in the proteomics era

A Fiser - Expert review of proteomics, 2004 - Taylor & Francis
Structural proteomics aims to understand the structural basis of protein interactions and
functions. A prerequisite for this is the availability of 3D protein structures that mediate the …

Protein structural bioinformatics: An overview

V de Almeida Paiva, I de Souza Gomes… - Computers in Biology …, 2022 - Elsevier
Proteins play a crucial role in organisms in nature. They are able to perform structural,
catalytic, transport and defense functions in cells, among others. We understand that a …

The Protein Model Portal—a comprehensive resource for protein structure and model information

J Haas, S Roth, K Arnold, F Kiefer, T Schmidt… - Database, 2013 - academic.oup.com
Abstract The Protein Model Portal (PMP) has been developed to foster effective use of 3D
molecular models in biomedical research by providing convenient and comprehensive …

PDBFlex: exploring flexibility in protein structures

T Hrabe, Z Li, M Sedova, P Rotkiewicz… - Nucleic acids …, 2016 - academic.oup.com
The PDBFlex database, available freely and with no login requirements at http://pdbflex. org,
provides information on flexibility of protein structures as revealed by the analysis of …

Advances in comparative protein-structure modelling

R Sanchez, A Šali - Current opinion in structural biology, 1997 - Elsevier
Comparative modelling of protein 3D structure can now be applied with reasonable
accuracy to ten times more protein sequences than the number of experimentally …