Optimization of hyaluronan-enriched cubosomes for bromfenac delivery enhancing corneal permeation: characterization, ex vivo, and in vivo evaluation
To design and evaluate hyaluronan-based cubosomes loaded with bromfenac sodium (BS)
for ocular application to enhance the corneal permeation and retention in pterygium and …
for ocular application to enhance the corneal permeation and retention in pterygium and …
[HTML][HTML] Chondroitin sulfate-chitosan nanoparticles for ocular delivery of bromfenac sodium: Improved permeation, retention, and penetration
Materials and Methods: Formulation was developed and optimized for CS, chondroitin, and
initial drug concentration. Optimized formulation was evaluated for various in vitro aspects …
initial drug concentration. Optimized formulation was evaluated for various in vitro aspects …
Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability
S Han, J Shen, Y Gan, H Geng, X Zhang… - Acta Pharmacologica …, 2010 - nature.com
Aim: To develop a novel vehicle based on cubosomes as an ophthalmic drug delivery
system for flurbiprofen (FB) to reduce ocular irritancy and improve bioavailability. Methods …
system for flurbiprofen (FB) to reduce ocular irritancy and improve bioavailability. Methods …
Gel in core carbosomes as novel ophthalmic vehicles with enhanced corneal permeation and residence
Carbopol is a good bio-adhesive polymer that increases the residence time in the eye.
However, the effect of blinking and lacrimation still reduce the amount of polymer and the …
However, the effect of blinking and lacrimation still reduce the amount of polymer and the …
[PDF][PDF] Fabrication and evaluation of ketorolac loaded cubosome for ocular drug delivery
Ophthalmic formulations in terms of eye drops are more frequently used formulation for
ocular disorders. But unfortunately this mode of drug instillation into the cul-de-sac of eye …
ocular disorders. But unfortunately this mode of drug instillation into the cul-de-sac of eye …
Hyalugel-integrated liposomes as a novel ocular nanosized delivery system of fluconazole with promising prolonged effect
Fungal infections need long-term therapy with the proper antifungal agent. Despite
effectiveness, Fluconazole (FLZ) ocular delivery is constrained by limited penetration, short …
effectiveness, Fluconazole (FLZ) ocular delivery is constrained by limited penetration, short …
Investigating nanostructured liquid crystalline particles as prospective ocular delivery vehicle for tobramycin sulfate: Ex vivo: and: in vivo: studies
Tobramycin remains the anchor drug for bacterial keratitis treatment and management;
however, unlike other aminoglycosides, it does not pass through the gastrointestinal tract …
however, unlike other aminoglycosides, it does not pass through the gastrointestinal tract …
Fabrication of novel ultradeformable bilosomes for enhanced ocular delivery of terconazole: in vitro characterization, ex vivo permeation and in vivo safety assessment
AA Abdelbary, WH Abd-Elsalam… - International journal of …, 2016 - Elsevier
The objective of this work was to encapsulate terconazole (TCZ), a water insoluble
antifungal drug, into novel ultradeformable bilosomes (UBs) for achieving enhanced ocular …
antifungal drug, into novel ultradeformable bilosomes (UBs) for achieving enhanced ocular …
Novel cubosome based system for ocular delivery of acetazolamide
Acetazolamide is the drug of choice for glaucoma treatment in an emergency. However, it is
not available in any topical formulation and it is available only as systemic tablets. Despite …
not available in any topical formulation and it is available only as systemic tablets. Despite …
Formulation and evaluation of cubosomes drug delivery system for treatment of glaucoma: Ex-vivo permeation and in-vivo pharmacodynamic study
Glaucoma, a chronic disease of elevated intraocular pressure, is considered as the first
leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular …
leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular …