Ganglioside G M3 is the predominant ganglioside of keratinocyte membranes. It has been
proposed in other cell types that G M3 may participate in the regulation of cell proliferation …

The altered patterns of expression of gangliosides during density-dependent growth
inhibition, oncogenic transformation, and embryogenesis suggest that gangliosides …

We examined the ganglioside content of normal human keratinocytes and basal cell
carcinomas (BCC). The total ganglioside content of the epidermis was 0.098±0.01 μg lipid …

The expression of GM3 In human skin fibroblasts (cell type MF II) was investigated
biochemically and immunochemically by means of the monoclonal antibody M2590. A cell …

We have selected G D3-deficient human melanoma cell lines, in order to investigate the
function of G D3 ganglioside. This was done by treating SK-MEL-28 cells with anti-G D3 …

Human skin melanocytes and melanocytes cultured in vitro express GM3 ganglioside almost
exclusively, whereas malignant melanomas express high levels of both GM3 and GD3. We …

Highly sialylated gangliosides have been shown to alter cellular adhesion to a fibronectin
matrix. The effect of these gangliosides on the adhesion, spreading, and migration of …

The expression of gangliosides in non-malignant tissues (epidermis and pigmented nevus)
and neoplastic lesions (melanoma, squamous cell carcinoma [SCC] and basal cell …

The biologic functions of gangliosides G M3 and G D3 in the attachment of human
melanoma cells to extracellular matrix proteins (type I and IV collagens, fibronectin, and …

An increased synthesis of the ganglioside GM2 has been reported on transformed murine
cells, human fetal tissues, and transformed melanocytes. This study was designed to …