Inflammatory-Targeted Lipid Carrier as a New Nanomaterial to Formulate an Inhaled Drug Delivery System

E Maretti, F Gioia, C Rustichelli, S Molinari, E Leo - Molecules, 2024 - mdpi.com
There is a pressing need for efficacious therapies in the field of respiratory diseases and
infections. Lipid nanocarriers, administered through aerosols, represent a promising tool for …

Lipid nanoparticles as delivery vehicles for inhaled therapeutics

EWX Leong, R Ge - Biomedicines, 2022 - mdpi.com
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …

[引用][C] Lipid Nanoparticles as Delivery Vehicles for Inhaled Therapeutics. Biomedicines 2022, 10, 2179

EWX Leong, R Ge - 2022 - europepmc.org
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …

Inhalable microparticle platform based on a novel shell-forming lipid excipient and its feasibility for respirable delivery of biologics

H Wang, P Connaughton, K Lachacz, N Carrigy… - European Journal of …, 2022 - Elsevier
Administration of biologics such as proteins, vaccines, and phages via the respiratory route
is becoming increasingly popular. Inhalable powder formulations for the successful delivery …

Lipid nanoplatforms for pulmonary drug delivery

BM Ponte, IS Santos, AS Macedo… - … and Drug Delivery …, 2016 - api.taylorfrancis.com
For drug administration and delivery design, it is important to consider a number of factors,
but mainly the drug form and the administration route. The most depends on the …

A Pilot Study Exploiting the Industrialization Potential of Solid Lipid Nanoparticle-Based Metered-Dose Inhalers

L Shu, W Wang, C Ng, X Zhang, Y Huang, C Wu, X Pan… - Pharmaceutics, 2023 - mdpi.com
Background: Delivery of inhalable nanoparticles through metered-dose inhalers (MDI) is a
promising approach to treat lung disease such as asthma and chronic obstructive pulmonary …

[引用][C] Inhaled lipid nanoparticles: a feasible tool for a challenging route

E Leo, E Maretti - Current Drug Delivery, 2024 - ingentaconnect.com
Inhaled delivery systems are promising tools for a safe administration of drugs in pulmonary
diseases. Two methods of administration to the lung can be distinguished: inhalation and …

Lipid-based particle engineering via spray-drying for targeted delivery of antibiotics to the lung

C Corzo, D Crvenjak, K Sotirov, JA Urich… - International Journal of …, 2023 - Elsevier
Pulmonary delivery of antibiotics for the treatment of tuberculosis provides several benefits
compared to conventional oral and parenteral administration. API-loaded particles delivered …

Microencapsulated solid lipid nanoparticles as a hybrid platform for pulmonary antibiotic delivery

DP Gaspar, MM Gaspar, CV Eleuterio… - Molecular …, 2017 - ACS Publications
Solid lipid nanoparticles (SLN) containing rifabutin (RFB), with pulmonary administration
purposes, were developed through a technique that avoids the use of organic solvents or …

Aerosol delivery of ferulic acid-loaded nanostructured lipid carriers: A promising treatment approach against the respiratory disorders

P Hassanzadeh, E Arbabi, F Rostami… - Physiology and …, 2017 - ppj.phypha.ir
Introduction: Treatment of lung diseases is one of the major healthcare challenges. Ferulic
acid (FA), a phenolic compound with well-established antioxidant and anti-inflammatory …