INTRODUCTION AND OBJECTIVES: Recent clinical studies suggest a potential
antiarrhythmic role of angiotensin-converting enzyme inhibitors in preventing atrial …

Atrial fibrillation (AF) is the most frequent sustained arrhythmia found in clinical practice. 1, 2
According to the Framingham Heart Study, AF has a prevalence of 4% in the adult …

Background—The blockade of angiotensin II (Ang II) formation has protective effects on
cardiovascular tissue; however, the role of Ang II in atrial electrical remodeling is unknown …

Objective: Atrial remodeling contributes to the maintenance of atrial fibrillation (AF) in
several cardiac disorders. There is evidence that angiotensin-converting enzyme (ACE) …

Objectives: The purpose of the present study was to evaluate the effect of angiotensin II type
1 receptor (AT1R) antagonist on chronic structural remodeling in atrial fibrillation (AF) …

BACKGROUND: Several studies have indicated that treatment with angiotensin converting
enzyme (ACE) inhibitors and angiotensin II type 1 receptor blockers (ARBs) may reduce the …

Introduction Angiotensin-receptor blockers may exert favourable anti-arrhythmic effects in
atrial fibrillation (AF), but their mechanisms are not fully understood. In this study, we tested …

We thank Professors Celik and Iyisoy for their comments on the Candesartan in the
Prevention of Relapsing Atrial Fibrillation (CAPRAF) study [1]. This was the first double blind …

Atrial fibrillation (AF) is a progressive disease and may be self-sustaining. The processes
that lead to the worsening of AF over time include electrical, contractile, neurohormonal …

Background Experimental studies suggest that angiotensin II-receptor blockers can
influence atrial remodeling and may prevent atrial fibrillation (AF). Therefore, we …