Platelets, extracellular vesicles and coagulation in pulmonary arterial hypertension

S Cullivan, CA Murphy, L Weiss… - Pulmonary …, 2021 - journals.sagepub.com
Pulmonary arterial hypertension is a rare disease of the pulmonary vasculature,
characterised pathologically by proliferation, remodelling and thrombosis in situ …

The role of platelets in the development and progression of pulmonary arterial hypertension

R Kazimierczyk, K Kamiński - Advances in medical sciences, 2018 - Elsevier
Pulmonary arterial hypertension is a multifactorial disease characterized by
vasoconstriction, vascular remodeling, inflammation and thrombosis. Although an increasing …

Pulmonary arterial hypertension

C Burt, J Pepke-Zaba, F Falter - Current Vascular …, 2010 - ingentaconnect.com
The last 10 years have seen significant advances in the understanding of the
pathophysiology and treatment of pulmonary arterial hypertension (PAH). This has included …

Pathobiology of pulmonary hypertension: the role of platelets and thrombosis

P Herve, M Humbert, O Sitbon… - Clinics in chest …, 2001 - chestmed.theclinics.com
Thrombosis and platelet dysfunction are potentially important pathophysiologic processes
that have been identified from descriptive studies from patients with pulmonary arterial …

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

M Humbert, C Guignabert, S Bonnet… - European …, 2019 - Eur Respiratory Soc
Clinical and translational research has played a major role in advancing our understanding
of pulmonary hypertension (PH), including pulmonary arterial hypertension and other forms …

Pulmonary hypertension: the science behind the disease spectrum

MR Wilkins - European Respiratory Review, 2012 - Eur Respiratory Soc
Pulmonary hypertension (PH) is a complex, multifactorial disorder divided into five major
subtypes according to pathological, pathophysiological and therapeutic characteristics …

[HTML][HTML] Beyond thrombosis: the role of platelets in pulmonary hypertension

S Nicoleau, B Wojciak-Stothard - SciMedicine Journal, 2020 - scimedjournal.org
Pulmonary Hypertension (PH) is a multifactorial and lethal disease, characterised by
elevated pulmonary arterial pressure and progressive right heart failure. PH pathobiology …

Thrombosis, platelets, microparticles and PAH: more than a clot

KL Lannan, RP Phipps, RJ White - Drug discovery today, 2014 - Elsevier
Highlights•Thrombosis and excess platelet activation are key pathologic features of
pulmonary arterial hypertension (PAH).•Platelets are the main source of circulating …

Pulmonary hypertension: Classification and pathobiology

LC Huber, B Vrugt, M Arrigo - Cardiovascular Medicine, 2014 - zora.uzh.ch
Pulmonary hypertension is defined as an increase of the mean pulmonary arterial pressure
above 25 mm Hg and, as such, the diagnosis requires invasive haemodynamic …

[HTML][HTML] Extracellular vesicles in pulmonary hypertension: a dangerous liaison?

M Conti, M Minniti, M Tiné, M De Francesco, R Gaeta… - Biology, 2023 - mdpi.com
Simple Summary This review discusses the role of extracellular vesicles in pulmonary
hypertension a serious and progressive lung disease characterized by high blood pressure …