Background Approximately 15 to 30% of thyroid nodules evaluated by means of fine-needle
aspiration are not clearly benign or malignant. Patients with cytologically indeterminate …

Objective To break out subcategories of atypical and suspicious cytologic interpretations of
thyroid aspirations and correlate those with final histologic diagnosis. Summary Background …

Background: Fine-needle aspiration remains the primary diagnostic intervention for the
evaluation of most thyroid nodules larger than 1–1.5 cm. Although most aspirates provide …

In accordance with National Guidelines, we currently follow a linear approach to the
diagnosis of thyroid nodules, with management decision based primarily on a cytological …

Objective Controversy surrounds the evaluation of nodules with indeterminate cytology
results. Malignancy rates in these nodules are not low. We examined the malignancy rates …

Importance Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have
indeterminate cytology, most frequently Bethesda category III or IV. Diagnostic surgeries can …

Background Controversy exists regarding the accuracy of fine-needle aspiration (FNA) in
large thyroid nodules. Recent surgical series have documented false-negative rates ranging …

BACKGROUND: The optimal management of cytologically indeterminate thyroid nodules is
controversial given the variable malignancy rates reported in this patient population. We …

Background: Seventy-five percent of thyroid nodules with indeterminate fine-needle
aspiration (FNA) cytology are found to be benign postoperatively. A novel genomic test, the …

Importance Use of next-generation sequencing of RNA and machine learning algorithms
can classify the risk of malignancy in cytologically indeterminate thyroid nodules to limit …