The protein menin is encoded by the MEN1 gene, which is mutated in patients with multiple
endocrine neoplasia type 1 (MEN1) syndrome. Although menin acts as a tumor suppressor …

Menin is a tumor suppressor that is mutated in patients with multiple endocrine neoplasia
type I (MEN1), an inherited tumor-prone syndrome. Because there is no obvious conserved …

The multiple endocrine neoplasia type 1 (MEN1) gene is a tumor suppressor gene encoding
a 610 amino acid nuclear protein, menin. Although mutations of the MEN1 gene are …

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disease predisposed
by heterozygous germline mutations in the MEN1 tumor suppressor gene. Biallelic loss of …

Since the discovery of the multiple endocrine neoplasia type 1 (MEN1) gene in 1997,
elucidation of the molecular function of its protein product, menin, has been a challenge …

Multiple endocrine neoplasia type I (MEN1) is a familial cancer syndrome characterized
primarily by tumors of multiple endocrine glands. The gene for MEN1 encodes a …

Human hereditary tumor syndromes serve as an ideal model for studying molecular
pathways regulating tumorigenesis. Multiple endocrine neoplasia type 1 (MEN1), a human …

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder associated
mainly with tumors of multiple endocrine organs. Mutations in the MEN1 gene that encodes …

MEN1 is a tumor suppressor gene that is responsible for multiple endocrine neoplasia type
1 (MEN1) and that encodes a 610-amino-acid protein, called menin. While the majority of …

Multiple endocrine neoplasia type I (MEN1), a hereditary tumor syndrome, is characterized
by the development of tumors in multiple endocrine organs. The gene mutated in MEN1 …