Microfluidic formulation of topological hydrogels for microtissue engineering

KO Rojek, M Cwiklinska, J Kuczak… - Chemical …, 2022 - ACS Publications
Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …

Designing microgels for cell culture and controlled assembly of tissue microenvironments

AS Caldwell, BA Aguado… - Advanced functional …, 2020 - Wiley Online Library
Micrometer‐sized hydrogels, termed microgels, are emerging as multifunctional platforms
that can recapitulate tissue heterogeneity in engineered cell microenvironments. The …

Cell-laden microfluidic microgels for tissue regeneration

W Jiang, M Li, Z Chen, KW Leong - Lab on a Chip, 2016 - pubs.rsc.org
Regeneration of diseased tissue is one of the foremost concerns for millions of patients who
suffer from tissue damage each year. Local delivery of cell-laden hydrogels offers an …

Microfluidics-based fabrication of cell-laden microgels

MGA Mohamed, P Ambhorkar, R Samanipour… - …, 2020 - pubs.aip.org
Microfluidic principles have been extensively utilized as powerful tools to fabricate controlled
monodisperse cell-laden hydrogel microdroplets for various biological applications …

Microfluidic templated multicompartment microgels for 3D encapsulation and pairing of single cells

L Zhang, K Chen, H Zhang, B Pang, CH Choi, AS Mao… - Small, 2018 - Wiley Online Library
Controlled encapsulation and pairing of single cells within a confined 3D matrix can enable
the replication of the highly ordered cellular structure of human tissues. Microgels with …

[PDF][PDF] Mosaic hydrogels: one‐step formation of multiscale soft materials

L Leng, A McAllister, B Zhang, M Radisic, A Günther - Advanced materials, 2012 - Citeseer
Soft materials with a spatially non-uniform composition that is closely linked to their function
are abundant in nature. Such materials often possess a hierarchical architecture that …

Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering

BG Chung, KH Lee, A Khademhosseini, SH Lee - Lab on a Chip, 2012 - pubs.rsc.org
Microfluidic technologies are emerging as an enabling tool for various applications in tissue
engineering and cell biology. One emerging use of microfluidic systems is the generation of …

High‐throughput fabrication and modular assembly of 3D heterogeneous microscale tissues

W Yang, H Yu, G Li, Y Wang, L Liu - Small, 2017 - Wiley Online Library
3D hydrogel microstructures that encapsulate cells have been used in broad applications in
microscale tissue engineering, personalized drug screening, and regenerative medicine …

Emerging technologies for assembly of microscale hydrogels

UA Gurkan, S Tasoglu, D Kavaz… - Advanced …, 2012 - Wiley Online Library
Assembly of cell encapsulating building blocks (ie, microscale hydrogels) has significant
applications in areas including regenerative medicine, tissue engineering, and cell‐based in …

Designing compartmentalized hydrogel microparticles for cell encapsulation and scalable 3D cell culture

YC Lu, W Song, D An, BJ Kim, R Schwartz… - Journal of Materials …, 2015 - pubs.rsc.org
We describe here designs of compartmentalized hydrogel microparticles with a tunable
extracellular matrix (ECM) support for cell encapsulation and scalable 3D cell culture. The …