Background In several reports, C3 and C4 have been linked to diabetes and cardiovascular
disease (CVD). Here, we investigate this link and the degree of C3 activation in elderly …

Aims Serum C3 is a powerful indicator of the risk of myocardial infarction, which correlates
with body mass index, serum lipids and blood pressure. This study was performed to …

Background: An intricate network of reciprocal interactions between adipose tissue and
immune system have been largely demonstrated, leading to the well-accepted concept of …

OBJECTIVE: To investigate the role of low-grade inflammation and insulin resistance
(HOMA2-IR) in adiposity-related increases in serum complement factor 3 (C3). Although C3 …

Abundant reports have shown that there is a strong relationship between C3 and C3a-
desArg levels, adipose tissue, and risk factors for cardiovascular disease, metabolic …

Introduction: Increased systemic inflammation plays a significant role in the development of
adult cardiometabolic diseases such as insulin resistance, dyslipidemia, atherosclerosis …

As the common factor linking adipose tissue to the metabolic context of obesity, insulin
resistance and atherosclerosis are associated with a low-grade chronic inflammatory status …

Objective Serum C3, a complement component produced by macrophages, the liver and the
adipose tissue, is associated with the risk of myocardial infarction in men. This study was …

Objective: Increased C3 has been related to body mass index (BMI) and insulin resistance,
although there are not sufficient studies in subjects with morbid obesity. The purpose of this …

The complement system has been implicated in obesity, fatty liver, diabetes and
cardiovascular disease (CVD). Complement factors are produced in adipose tissue and …