The absorption of drugs into the nail unit, following topical application to the nail plate, is
highly desirable to treat nail disorders, such as onychomycosis (fungal infections of the nail) …

The topical therapy of nail diseases, especially of onychomycosis, and to a smaller extent, of
nail psoriasis, is desirable to avoid the side effects associated with their systemic therapy, to …

Topical therapy is highly desirable in treating nail disorders due to its localized effects, which
results in minimal adverse systemic events and possibly improved adherence. However, the …

The human nail plate is a formidable barrier to drug permeation. Development of
therapeutics for management of nail diseases thus remains a challenge. This article reviews …

Topical therapy is desirable in treatment of nail diseases like onychomycosis (fungal
infection of nail) and psoriasis. The topical treatment avoids the adverse effects associated …

Topical therapy is at the forefront in treating nail ailments (especially onychomycosis and
nail psoriasis) due to its local effects, which circumvents systemic adverse events, improves …

The objectives of the present study are to clarify the relationship between the
physicochemical properties and the nail permeability of drugs through human nail plates …

Onychomycosis accounts for 50% of all nail disease cases and is commonly caused by
dermatophytes. It was primarily considered a cosmetic problem but has been garnering …

The treatment of onychomycosis remains problematic even though there are several potent
antifungal agents available for patient use. The aim of this investigation was to understand …

The topical therapy of nail diseases is limited by the low permeability of drugs through the
nail plate. To increase drug penetration, the integrity of the nail plate must be compromised …