[HTML][HTML] Recent developments in bio-scaffold materials as delivery strategies for therapeutics for endometrium regeneration

X Li, HF Lv, R Zhao, M Ying, AT Samuriwo, YZ Zhao - Materials Today Bio, 2021 - Elsevier
Intrauterine adhesions (IUAs) refer to the repair disorder after endometrial injury and may
lead to uterine infertility, recurrent miscarriage, abnormal menstrual bleeding, and other …

Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion

J Ma, H Zhan, W Li, L Zhang, F Yun, R Wu, J Lin… - Biomaterials …, 2021 - Springer
Intrauterine adhesion (IUA) is a common gynaecological disease that develops from
infection or trauma. IUA disease may seriously affect the physical and mental health of …

[HTML][HTML] Research progress of stem cell therapy for endometrial injury

J Cen, Y Zhang, Y Bai, S Ma, C Zhang, L Jin, S Duan… - Materials Today Bio, 2022 - Elsevier
Endometrial damage is an important factor leading to infertility and traditional conventional
treatments have limited efficacy. As an emerging technology in recent years, stem cell …

A collagen scaffold loaded with human umbilical cord-derived mesenchymal stem cells facilitates endometrial regeneration and restores fertility

L Xin, X Lin, Y Pan, X Zheng, L Shi, Y Zhang, L Ma… - Acta biomaterialia, 2019 - Elsevier
In women of reproductive age, severe injuries to the endometrium are often accompanied by
endometrial scar formation or intrauterine adhesions (IUAs), which can result in infertility or …

An acellular scaffold facilitates endometrial regeneration and fertility restoration via recruiting endogenous mesenchymal stem cells

L Xin, X Zheng, J Chen, S Hu, Y Luo… - Advanced …, 2022 - Wiley Online Library
Severe intrauterine adhesions (IUAs), characterized by inadequate endometrial repair and
fibrosis, can lead to infertility. Stem cell‐based therapies, which deliver mesenchymal stem …

Advanced biomaterials for promoting endometrial regeneration

Z Yin, J Wang, W Cui, C Tong - Advanced Healthcare Materials, 2023 - Wiley Online Library
The endometrium, as the innermost structure of the uterine cavity, plays a direct role in the
implantation of the fertilized egg, its conception, and the formation of normal menstruation. In …

[HTML][HTML] Recent developments in biomaterial-based hydrogel as the delivery system for repairing endometrial injury

G Cai, Z Hou, W Sun, P Li, J Zhang, L Yang… - … in Bioengineering and …, 2022 - frontiersin.org
Endometrial injury caused by intrauterine surgery often leads to pathophysiological changes
in the intrauterine environment, resulting in infertility in women of childbearing age …

Functionalized human umbilical cord mesenchymal stem cells and injectable HA/Gel hydrogel synergy in endometrial repair and fertility recovery

D Zhang, Q Du, C Li, C Ding, J Chen, Y He, T Duan… - Acta Biomaterialia, 2023 - Elsevier
Intrauterine adhesions (IUA) caused by endometrial injury are one of the main causes of
female infertility. The current treatments for endometrial injury offer limited clinical benefits …

PGS scaffolds promote the in vivo survival and directional differentiation of bone marrow mesenchymal stem cells restoring the morphology and function of wounded …

B Xiao, W Yang, D Lei, J Huang, Y Yin… - Advanced …, 2019 - Wiley Online Library
Intrauterine adhesion (IUA) causing infertility and recurrent miscarriage of reproductive
female mammals usually results from endometrium injury. Nevertheless, there is no efficient …

An injectable gelatin/sericin hydrogel loaded with human umbilical cord mesenchymal stem cells for the treatment of uterine injury

L Chen, L Li, Q Mo, X Zhang, C Chen… - Bioengineering & …, 2023 - Wiley Online Library
Abnormal endometrial receptivity is a major cause of the failure of embryo transplantation,
which may lead to infertility, adverse pregnancy, and neonatal outcomes. While hormonal …