Studies on the mechanisms of leukocyte adhesion to cellulose acetate beads: an in vitro model to assess the efficacy of cellulose acetate carrier‐based granulocyte …

K Hiraishi, Y Takeda, N Shiobara… - Therapeutic …, 2003 - Wiley Online Library
Granulocyte and monocyte adsorptive apheresis (GMA) using a column filled with cellulose
acetate (CA) beads (carriers) has been associated with a significant clinical efficacy in …

Cellulose acetate beads induce release of interleukin-1 receptor antagonist, but not tumour necrosis factor-α or interleukin-1β in human peripheral blood

Y Takeda, K Hiraishi, H Takeda, N Shiobara… - Inflammation …, 2003 - Springer
Objective: Dramatic improvements in clinical symptoms of rheumatoid arthritis and ulcerative
colitis were observed after patients received granulocyte and monocyte adsorptive …

Adacolumn, an Adsorptive Carrier Based Granulocyte and MonocyteApheresis Device for the Treatment of Inflammatory and RefractoryDiseases Associated with …

AR Saniabadi, H Hanai, K Takeuchi… - Therapeutic …, 2003 - Wiley Online Library
Apheresis has been recognized both economically and therapeuticallyas a novel approach
for the treatment of inflammatory diseases, and certain others, which respond poorly to drug …

Adhesion dependent release of hepatocyte growth factor and interleukin-1 receptor antagonist from human blood granulocytes and monocytes: evidence for the …

Y Takeda, N Shiobara, AR Saniabadi, M Adachi… - Inflammation …, 2004 - Springer
Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

Immunomodulatory effects of granulocyte and monocyte adsorption apheresis as a treatment for patients with ulcerative colitis

N Kashiwagi, K Sugimura, H Koiwai… - Digestive diseases and …, 2002 - Springer
Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …

Granulocyte and monocyte adsorption apheresis for refractory skin diseases due to activated neutrophils, psoriasis, and associated arthropathy

M Sakanoue, K Takeda, K Kawai… - … Apheresis and Dialysis, 2013 - Wiley Online Library
Granulocyte and monocyte adsorption apheresis (GMA), an extracorporeal apheresis
instrument whose column contains cellulose acetate (CA) beads, is designed to remove …

Granulocyte and monocyte adsorption apheresis (GCAP) for refractory skin diseases caused by activated neutrophils and psoriatic arthritis: evidence that GCAP …

T Kanekura, K Hiraishi, K Kawahara… - Therapeutic …, 2006 - Wiley Online Library
In the present study, we have shown that granulocyte and monocyte adsorption apheresis
(GCAP), an extracorporeal apheresis instrument whose column contains cellulose acetate …

Anti-inflammatory effect of granulocyte and monocyte adsorption apheresis in a rabbit model of immune arthritis

N Kashiwagi, M Nakano, AR Saniabadi, M Adachi… - Inflammation, 2002 - Springer
In active rheumatoid arthritis, large numbers of granulocytes and macrophages are found in
the inflamed joints. These leucocytes can promote inflammation and tissue injury by …

In vitro and in vivo evaluation of Adacolumn® cytapheresis in healthy subjects

W Ramlow, J Emmrich, P Ahrenholz… - Journal of Clinical …, 2005 - Wiley Online Library
Adacolumn® is a medical device for adsorptive cytapheresis. It has been developed for
selective adsorption of granulocytes and monocytes from peripheral blood of patients with …

Clinical and immunological effects of adsorptive myeloid lineage leukocyte apheresis in patients with immune disorders

T Kanekura - The Journal of Dermatology, 2018 - Wiley Online Library
Adsorptive granulocyte and monocyte apheresis (GMA) with the Adacolumn® is an
extracorporeal treatment, which uses cellulose acetate (CA) beads as adsorptive …