Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death
worldwide and has few effective therapies. It is characterized by anomalous and persistent …

Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous collection of
conditions characterized by irreversible expiratory airflow limitation. The disease involves a …

Current paradigms of chronic obstructive pulmonary disease (COPD) treatment suggest
stratifying patients by their symptoms, utilising three main drug classes, but it is unclear if this …

Chronic obstructive pulmonary disease (COPD) is characterized by a decreased airflow due
to airway narrowing that, once it occurs, is not fully reversible. The disease usually is …

Airway neutrophilia is a common feature of many chronic inflammatory lung diseases and is
associated with disease progression, often regardless of the initiating cause. Neutrophils …

Chronic obstructive pulmonary disease (COPD) is a common, progressive and debilitating
chronic inflammatory condition affecting the lungs, with significant systemic manifestations …

Rationale: Patients with chronic obstructive pulmonary disease (COPD) experience excess
cardiovascular morbidity and mortality, and exacerbations further increase the risk of such …

BACKGROUND Neutrophils are likely to play a major role in the inflammatory response
seen in chronic obstructive pulmonary disease (COPD). This study sought to address the …

Neutrophils have the capacity to accumulate in high numbers in the lung during infection
and inflammation. Because they play an important role in host defence against infection, but …

Many lung diseases are characterized by neutrophil-dominated inflammation; therefore, an
understanding of neutrophil function is of considerable importance to respiratory physicians …