Common misconceptions, hidden biases and modern challenges of dMRI tractography

F Rheault, P Poulin, AV Caron, E St-Onge… - Journal of neural …, 2020 - iopscience.iop.org
The human brain is a complex and organized network, where the connection between
regions is not achieved with single axons crisscrossing each other but rather millions of …

Diffusion MRI-based cortical connectome reconstruction: dependency on tractography procedures and neuroanatomical characteristics

MRT Sinke, WM Otte, D Christiaens, O Schmitt… - Brain Structure and …, 2018 - Springer
Diffusion MRI (dMRI)-based tractography offers unique abilities to map whole-brain
structural connections in human and animal brains. However, dMRI-based tractography …

Ax T ract: Toward microstructure informed tractography

G Girard, A Daducci, L Petit, JP Thiran… - Human brain …, 2017 - Wiley Online Library
Diffusion‐weighted (DW) magnetic resonance imaging (MRI) tractography has become the
tool of choice to probe the human brain's white matter in vivo. However, tractography …

Human cortical connectome reconstruction from diffusion weighted MRI: the effect of tractography algorithm

M Bastiani, NJ Shah, R Goebel, A Roebroeck - Neuroimage, 2012 - Elsevier
Reconstructing the macroscopic human cortical connectome by Diffusion Weighted Imaging
(DWI) is a challenging research topic that has recently gained a lot of attention. In the …

Microstructure informed tractography: pitfalls and open challenges

A Daducci, A Dal Palú, M Descoteaux… - Frontiers in …, 2016 - frontiersin.org
One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by
existing algorithms are not truly quantitative. Local techniques for estimating more …

Limits to anatomical accuracy of diffusion tractography using modern approaches

KG Schilling, V Nath, C Hansen, P Parvathaneni… - Neuroimage, 2019 - Elsevier
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the
brain, with a range of applications in both clinical and basic neuroscience. Despite …

[HTML][HTML] Quantitative mapping of the brain's structural connectivity using diffusion MRI tractography: A review

F Zhang, A Daducci, Y He, S Schiavi, C Seguin… - Neuroimage, 2022 - Elsevier
Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …

[HTML][HTML] Using diffusion MRI data acquired with ultra-high gradient strength to improve tractography in routine-quality data

C Maffei, C Lee, M Planich, M Ramprasad, N Ravi… - Neuroimage, 2021 - Elsevier
The development of scanners with ultra-high gradient strength, spearheaded by the Human
Connectome Project, has led to dramatic improvements in the spatial, angular, and diffusion …

Prevalence of white matter pathways coming into a single white matter voxel orientation: The bottleneck issue in tractography

KG Schilling, CMW Tax, F Rheault… - Human brain …, 2022 - Wiley Online Library
Characterizing and understanding the limitations of diffusion MRI fiber tractography is a
prerequisite for methodological advances and innovations which will allow these techniques …

Mapping connectomes with diffusion MRI: deterministic or probabilistic tractography?

T Sarwar, K Ramamohanarao… - Magnetic resonance in …, 2019 - Wiley Online Library
Purpose Human connectomics necessitates high‐throughput, whole‐brain reconstruction of
multiple white matter fiber bundles. Scaling up tractography to meet these high‐throughput …