A framework for the systematic selection of biosensor chassis for environmental synthetic biology

S Sridhar, CM Ajo-Franklin, CA Masiello - ACS Synthetic Biology, 2022 - ACS Publications
Microbial biosensors sense and report exposures to stimuli, thereby facilitating our
understanding of environmental processes. Successful design and deployment of …

Programming living sensors for environment, health and biomanufacturing

X Wan, B Saltepe, L Yu, B Wang - Microbial biotechnology, 2021 - Wiley Online Library
Synthetic biology offers new tools and capabilities of engineering cells with desired
functions for example as new biosensing platforms leveraging engineered microbes. In the …

Translating new synthetic biology advances for biosensing into the earth and environmental sciences

I Del Valle, EM Fulk, P Kalvapalle, JJ Silberg… - Frontiers in …, 2021 - frontiersin.org
The rapid diversification of synthetic biology tools holds promise in making some classically
hard-to-solve environmental problems tractable. Here we review longstanding problems in …

Microbial-derived biosensors for monitoring environmental contaminants: Recent advances and future outlook

M Bilal, HMN Iqbal - Process Safety and Environmental Protection, 2019 - Elsevier
Living cells have evolved to sense various environmental stimuli, thus presenting a novel
platform to engineer bio-sensing devices. Owing to the ease of genetic modification and …

Design and fabrication of field-deployable microbial biosensing devices

HL Pham, H Ling, MW Chang - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Biosensing devices integrate synthetic biosensors with deployment
platforms.•Microbial sensing devices enable remote sensing and minimal-instrument …

Towards engineering biological systems in a broader context

OS Venturelli, RG Egbert, AP Arkin - Journal of molecular biology, 2016 - Elsevier
Significant advances have been made in synthetic biology to program information
processing capabilities in cells. While these designs can function predictably in controlled …

Synthetic gene circuits enable systems-level biosensor trigger discovery at the host-microbe interface

AD Naydich, SN Nangle, JJ Bues, D Trivedi, N Nissar… - …, 2019 - Am Soc Microbiol
Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to in vivo
signals is a promising new approach for the diagnosis, treatment, and prevention of disease …

Microbially derived biosensors for diagnosis, monitoring and epidemiology

HJ Chang, PL Voyvodic, A Zúñiga… - Microbial …, 2017 - Wiley Online Library
Living cells have evolved to detect and process various signals and can self‐replicate,
presenting an attractive platform for engineering scalable and affordable biosensing …

Genetically engineered microbial biosensors for in situ monitoring of environmental pollution

HJ Shin - Applied Microbiology and Biotechnology, 2011 - Springer
Microbial biosensors are compact, portable, cost effective, and simple to use, making them
seem eminently suitable for the in situ monitoring of environmental pollution. One promising …

Stability, robustness, and containment: preparing synthetic biology for real-world deployment

S Kumar, J Hasty - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•Environmentally responsive survival circuitry enable synthetic cell containment.•
Increased genetic stability by engineering sequence and host context.•Control circuits for …