Evidence accumulates: patients with ascending aneurysms are strongly protected from atherosclerotic disease

C Waldron, MA Zafar, BA Ziganshin… - International journal of …, 2023 - mdpi.com
Ascending thoracic aortic aneurysms may be fatal upon rupture or dissection and remain a
leading cause of death in the developed world. Understanding the pathophysiology of the …

Silver lining in the dark cloud of aneurysm disease

KH Chau, JR Bender, JA Elefteriades - Cardiology, 2014 - karger.com
An ascending aortic aneurysm is a common and very much unwelcome diagnosis that has
never been associated with anything positive. We believe, however, that there actually is a …

Ascending thoracic aneurysms are associated with decreased systemic atherosclerosis

H Achneck, B Modi, C Shaw, J Rizzo, G Albornoz… - Chest, 2005 - Elsevier
Study objectives We noted clinically that patients with aortic root aneurysms and dissections
seemed to have little systemic atherosclerosis. It is our objective to determine whether there …

Pathobiology of idiopathic ascending aortic aneurysms

EWM Kirsch, NC Radu, E Allaire… - … and Thoracic Annals, 2006 - journals.sagepub.com
The majority of ascending aortic aneurysms cannot be related to any specific etiology and
should be qualified as idiopathic. The pathobiology of ascending aortic aneurysms remains …

Aortic aneurysms: current pathogenesis and therapeutic targets

MJ Cho, MR Lee, JG Park - Experimental & Molecular Medicine, 2023 - nature.com
Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …

Molecular and cellular mechanisms involved in aortic wall aneurysm development

I Bararu Bojan, CE Pleșoianu, OV Badulescu… - Diagnostics, 2023 - mdpi.com
Aortic aneurysms represent a very common pathology that can affect any segment of the
aorta. These types of aneurysms can be localized on the thoracic segment or on the …

Ascending thoracic aortic aneurysms protect against myocardial infarctions

K Chau, JA Elefteriades - International Journal of Angiology, 2014 - thieme-connect.com
There has been increasing evidence that ascending thoracic aortic aneurysms (TAAs)
protect against atherosclerosis. However, there have been no studies examining the …

Accentuating and opposing factors leading to development of thoracic aortic aneurysms not due to genetic or inherited conditions

SW Rabkin - Frontiers in Cardiovascular Medicine, 2015 - frontiersin.org
Understanding and unraveling the pathophysiology of thoracic aortic aneurysm (TAA), a
vascular disease with a potentially high-mortality rate, is one of the next frontiers in vascular …

Risk of aortic dissection in patients with ascending aorta aneurysm: A new biological, morphological, and biomechanical network behind the aortic diameter

C Pisano, CR Balistreri, P Nardi, C Altieri, F Bertoldo… - Vessel Plus, 2020 - art.torvergata.it
Thoracic aortic aneurysm represents a deadly condition, particularly when it evolves into
rupture and dissection. Proper surgical timing is the key to positively influencing the survival …

Carotid intima-media thickness provides evidence that ascending aortic aneurysm protects against systemic atherosclerosis

A Hung, M Zafar, S Mukherjee, M Tranquilli, LM Scoutt… - Cardiology, 2012 - karger.com
Previous evaluation of total aortic calcium score suggests that mutations promoting
ascending aortic aneurysm development may protect against atherosclerosis. However …