Adult bone marrow–derived cells for cardiac repair: a systematic review and meta-analysis

A Abdel-Latif, R Bolli, IM Tleyjeh… - Archives of internal …, 2007 - jamanetwork.com
Background The results from small clinical studies suggest that therapy with adult bone
marrow (BM)–derived cells (BMCs) reduces infarct size and improves left ventricular function …

Adult bone marrow cell therapy for ischemic heart disease: evidence and insights from randomized controlled trials

MR Afzal, A Samanta, ZI Shah… - Circulation …, 2015 - Am Heart Assoc
Rationale: Notwithstanding the uncertainties about the outcomes of bone marrow cell (BMC)
therapy for heart repair, further insights are critically needed to improve this promising …

Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis

V Jeevanantham, M Butler, A Saad, A Abdel-Latif… - Circulation, 2012 - Am Heart Assoc
Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …

Intracoronary bone marrow–derived progenitor cells in acute myocardial infarction

V Schächinger, S Erbs, A Elsässer… - … England Journal of …, 2006 - Mass Medical Soc
Background Pilot trials suggest that the intracoronary administration of autologous
progenitor cells may improve left ventricular function after acute myocardial infarction …

[HTML][HTML] Role of adult bone marrow stem cells in the repair of ischemic myocardium: current state of the art

S Charwat, M Gyöngyösi, I Lang, S Graf, G Beran… - Experimental …, 2008 - Elsevier
OBJECTIVE: To review the milestones in stem cell therapy for ischemic heart disease from
early basic science to large clinical studies and new therapeutic approaches. MATERIALS …

Red blood cell contamination of the final cell product impairs the efficacy of autologous bone marrow mononuclear cell therapy

B Assmus, T Tonn, FH Seeger, CH Yoon… - Journal of the American …, 2010 - jacc.org
Objectives: The aim of this study was to identify an association between the quality and
functional activity of bone marrow-derived progenitor cells (BMCs) used for cardiovascular …

Promise of blood-and bone marrow-derived stem cell transplantation for functional cardiac repair: putting it in perspective with existing therapy

T Reffelmann, S Könemann, RA Kloner - Journal of the American College …, 2009 - jacc.org
Intracoronary transplantation of peripheral blood-or bone marrow-derived cells, as tested in
several recent trials, is associated with moderate increases in left ventricular (LV) ejection …

Effects of intracoronary autologous bone marrow cells on left ventricular function in acute myocardial infarction: a systematic review and meta-analysis for randomized …

S Kang, Y Yang, C Li, R Gao - Coronary artery disease, 2008 - journals.lww.com
Background Experimental and clinical studies have suggested that intracoronary infusion of
bone marrow-derived stem/progenitor cells (BMC) may improve left ventricular function after …

Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes

DM Clifford, SA Fisher, SJ Brunskill, C Doree, A Mathur… - PloS one, 2012 - journals.plos.org
Aims To investigate whether there are important sources of heterogeneity between the
findings of different clinical trials which administer autologous stem cell treatment for acute …

Clinical outcome 2 years after intracoronary administration of bone marrow–derived progenitor cells in acute myocardial infarction

B Assmus, A Rolf, S Erbs, A Elsässer… - Circulation: Heart …, 2010 - Am Heart Assoc
Background—The aim of this study was to investigate the clinical outcome 2 years after
intracoronary administration of autologous progenitor cells in patients with acute myocardial …