Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute …

E Estey, M De Lima, R Tibes, S Pierce, H Kantarjian… - Blood, 2007 - ashpublications.org
To prospectively assess the applicability of reduced-intensity conditioning hematopoietic
stem cell transplantation (RIC-HSCT), we wrote a protocol in which all untreated patients 50 …

Effect of age on outcome of reduced-intensity hematopoietic cell transplantation for older patients with acute myeloid leukemia in first complete remission or with …

BL McClune, DJ Weisdorf, TL Pedersen… - Journal of Clinical …, 2010 - ascopubs.org
Purpose Acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS)
primarily afflict older individuals. Hematopoietic cell transplantation (HCT) is generally not …

Reduced intensity compared with high dose conditioning for allotransplantation in acute myeloid leukemia and myelodysplastic syndrome: a comparative clinical …

CM Flynn, B Hirsch, T DeFor, JN Barker… - American journal of …, 2007 - Wiley Online Library
We evaluated the efficacy of hematopoietic stem cell transplantation (HSCT) using reduced
intensity (RI) vs. myeloablative (MA) conditioning for patients with acute myeloid leukemia …

[HTML][HTML] Outcome of allogeneic hematopoietic stem cell transplantation in patients age> 69 years with acute myelogenous leukemia: on behalf of the Acute Leukemia …

O Ringdén, A Boumendil, M Labopin, J Canaani… - Biology of Blood and …, 2019 - Elsevier
Reduced-intensity conditioning (RIC) allows for the use of allogeneic hematopoietic stem
cell transplantation (HSCT) in older patients with acute myelogenous leukemia (AML). We …

Phase II study of allogeneic transplantation for older patients with acute myeloid leukemia in first complete remission using a reduced-intensity conditioning regimen …

SM Devine, K Owzar, W Blum, F Mulkey… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Long-term survival rates for older patients with newly diagnosed acute myeloid
leukemia (AML) are extremely low. Previous observational studies suggest that allogeneic …

[HTML][HTML] Allogeneic hematopoietic stem cell transplantation for the treatment of high-risk acute myelogenous leukemia and myelodysplastic syndrome using reduced …

B Oran, S Giralt, R Saliba, C Hosing, U Popat… - Biology of Blood and …, 2007 - Elsevier
Reduced-intensity conditioning has extended the use of allogeneic hematopoietic stem cell
transplantation (HSCT) to patients otherwise not eligible for this treatment due to older age …

[HTML][HTML] Results of a phase III randomized, multi-center study of allogeneic stem cell transplantation after high versus reduced intensity conditioning in patients with …

BL Scott, MC Pasquini, B Logan, J Wu, S Devine… - Blood, 2015 - Elsevier
Although reduced intensity conditioning (RIC) has a lower toxicity profile and lower
treatment related mortality (TRM), retrospective analyses have shown higher relapse rates …

Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous …

R Martino, MD Caballero… - Blood, The Journal …, 2002 - ashpublications.org
We report the results of a prospective study of a reduced-intensity conditioning (RIC)
regimen followed by allogeneic peripheral blood stem cell transplantation (PBSCT) from an …

[HTML][HTML] Reduced intensity conditioning allogeneic hematopoietic cell transplantation for adult acute myeloid leukemia in complete remission-a review from the Acute …

S Sengsayadeth, BN Savani, D Blaise, F Malard… - …, 2015 - ncbi.nlm.nih.gov
Acute myeloid leukemia is the most common indication for an allogeneic hematopoietic cell
transplant. The introduction of reduced intensity conditioning has expanded the recipient …

Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free …

S Tauro, C Craddock, K Peggs, G Begum… - Journal of Clinical …, 2005 - ascopubs.org
Purpose The toxicity of allogeneic stem-cell transplantation can be substantially reduced
using a reduced-intensity conditioning (RIC) regimen. This has increased the proportion of …