The aim of this study was to investigate the antidepressant properties of stigmas and corms
of Crocus sativus L. The aqueous ethanol extract of C. sativus corms was fractionated on the …

As in traditional medicine, saffron is used as exhilarating agent and also our previous study
showed the antidepressant effect of saffron extracts, in this study, the effects of aqueous and …

The effects of aqueous and ethanolic extracts of Crocus sativus L. stigma and their
constituents safranal and crocin were studied for the antidepressant activity using forced …

Objective: The present study was designed to investigate the putative antidepressant effects
of crocin and crocetin, two major active ingredients of Crocus sativus L.(saffron) using mice …

The effects of aqueous and ethanolic extracts of CROCUS SATIVUS stigma and petal were
studied for the antidepressant activity according to the forced swimming test in mice. The …

The antidepressant activity of kaempferol, a Crocus sativus petal constituent, was evaluated
using forced swimming test in mice and rat. Fluoxetine (20 mg/kg), as a positive control, and …

Depression is a serious disorder in today's society, with estimates of lifetime prevalence as
high as 21% of the general population in some developed countries. As a therapeutic plant …

Depression is one of the most common neuropsychiatric conditions, with a lifetime
prevalence approaching 17%. Although a variety of pharmaceutical agents is available for …

Depressive disorders are very common in clinical practice, with approximately 11.3 of all
adults afflicted during any a year. Saffron is the world's most expensive spice and apart from …

Saffron stigma (Crocus sativus L.) is used for insomnia and anxiety in traditional medicine. In
this study, the anxiolytic and hypnotic effects of saffron aqueous extract and its constituents …