[HTML][HTML] Sleep deprivation aggravates brain injury after experimental subarachnoid hemorrhage via TLR4-MyD88 pathway
YP Xu, YN Tao, YP Wu, J Zhang, W Jiao… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Subarachnoid hemorrhage (SAH) is a life-threatening cerebrovascular disease, and most of
the SAH patients experience sleep deprivation during their hospital stay. It is well-known that …
the SAH patients experience sleep deprivation during their hospital stay. It is well-known that …
Obstructive sleep apnea aggravates neuroinflammation and pyroptosis in early brain injury following subarachnoid hemorrhage via ASC/HIF-1α pathway
J Xu, Q Li, CY Xu, S Mao, JJ Jin, W Gu… - Neural Regeneration …, 2022 - journals.lww.com
Obstructive sleep apnea can worsen the prognosis of subarachnoid hemorrhage. However,
the underlying mechanism remains unclear. In this study, we established a mouse model of …
the underlying mechanism remains unclear. In this study, we established a mouse model of …
Melatonin regulates apoptosis and autophagy via ROS-MST1 pathway in subarachnoid hemorrhage
Compelling evidence has indicated that imbalance between apoptosis and autophagy may
be involved in subarachnoid hemorrhage (SAH). We aimed to investigate the effects and …
be involved in subarachnoid hemorrhage (SAH). We aimed to investigate the effects and …
TLR2 antagonism attenuates the hippocampal neuronal damage in a murine model of sleep apnea via inhibiting neuroinflammation and oxidative stress
Y Deng, K Liu, Y Pan, J Ren, J Shang, L Chen… - Sleep and Breathing, 2020 - Springer
Background Obstructive sleep apnea (OSA) in humans chronically promotes the neuronal
damage in the hippocampus. Toll-like receptor 2 (TLR2) is pivotal for the development of …
damage in the hippocampus. Toll-like receptor 2 (TLR2) is pivotal for the development of …
Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experimental subarachnoid hemorrhage: possible involvement of TLR 4 …
Z Wang, L Wu, W You, C Ji… - Journal of pineal research, 2013 - Wiley Online Library
Previous studies proved that melatonin protected against secondary brain damage by
modulating oxidative stress after experimental subarachnoid hemorrhage (SAH), but it has …
modulating oxidative stress after experimental subarachnoid hemorrhage (SAH), but it has …
Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
S Cao, S Shrestha, J Li, X Yu, J Chen, F Yan, G Ying… - Scientific Reports, 2017 - nature.com
The NLRP3 inflammasome is activated in the early period following subarachnoid
hemorrhage (SAH), resulting in inflammatory responses. Recent studies have shown that …
hemorrhage (SAH), resulting in inflammatory responses. Recent studies have shown that …
[PDF][PDF] Melatonin attenuates white matter injury via reducing oligodendrocyte apoptosis after subarachnoid hemorrhage in mice
D Liu, Y Dong, G Li, Z Zou, G Hao, H Feng… - Turk …, 2020 - turkishneurosurgery.org.tr
ABSTRACT AIM: To determine whether melatonin (MLT) mitigates white matter (WM) injury
by attenuating NOD-like receptor family pyrin domain-containing 3 (NLRP3)-associated …
by attenuating NOD-like receptor family pyrin domain-containing 3 (NLRP3)-associated …
Melatonin attenuates early brain injury via the melatonin receptor/Sirt1/NF-κB signaling pathway following subarachnoid hemorrhage in mice
L Zhao, H Liu, L Yue, J Zhang, X Li, B Wang, Y Lin… - Molecular …, 2017 - Springer
Melatonin (Mel) has been reported to alleviate early brain injury (EBI) following
subarachnoid hemorrhage (SAH). The activation of silent information regulator 1 (Sirt1), a …
subarachnoid hemorrhage (SAH). The activation of silent information regulator 1 (Sirt1), a …
[HTML][HTML] Mild hypothermia alleviates early brain injury after subarachnoid hemorrhage via suppressing pyroptosis through AMPK/NLRP3 inflammasome pathway in …
Z Zhou, Z Liu, C Zhang, W Zhang, C Zhang… - Brain Research …, 2023 - Elsevier
As a subtype of stroke, subarachnoid hemorrhage (SAH) has a notoriously high rate of
disability and mortality owing to the lack of effective intervention. Early brain injury (EBI) is …
disability and mortality owing to the lack of effective intervention. Early brain injury (EBI) is …
Activation of the Hippocampal DRD2 Alleviates Neuroinflammation, Synaptic Plasticity Damage and Cognitive Impairment After Sleep Deprivation
H Gao, Y Zhang, D Luo, J Xu, S Tan, Y Li, W Qi… - Molecular …, 2023 - Springer
Sleep loss is commonplace nowadays and profoundly impacts cognition. Dopamine
receptor D2 (DRD2) makes a specific contribution to cognition, although the precise …
receptor D2 (DRD2) makes a specific contribution to cognition, although the precise …
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