[HTML][HTML] Endothelial dysfunction, inflammation and coronary artery disease: potential biomarkers and promising therapeutical approaches

DJ Medina-Leyte, O Zepeda-García… - International journal of …, 2021 - mdpi.com
Coronary artery disease (CAD) and its complications are the leading cause of death
worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the …

[HTML][HTML] Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease

W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are disorders associated with the heart and circulatory
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …

[HTML][HTML] Endothelial dysfunction in chronic inflammatory diseases

CM Steyers III, FJ Miller Jr - International journal of molecular sciences, 2014 - mdpi.com
Chronic inflammatory diseases are associated with accelerated atherosclerosis and
increased risk of cardiovascular diseases (CVD). As the pathogenesis of atherosclerosis is …

[HTML][HTML] Biomarkers of endothelial activation and dysfunction in cardiovascular diseases

J Zhang - Reviews in cardiovascular medicine, 2022 - imrpress.com
Endothelial activation and dysfunction is an important contributor to atherosclerosis,
cardiovascular diseases and cardiorenal syndrome. Endothelial dysfunction is also linked …

Endothelial cell dysfunction as a novel therapeutic target in atherosclerosis

HA Jensen, JL Mehta - Expert review of cardiovascular therapy, 2016 - Taylor & Francis
Introduction: Dysfunction of vessel endothelium is the first step in a complex and multi-
faceted process that eventually leads to initiation of the plaque, formation of atherosclerotic …

[HTML][HTML] Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Endothelial dysfunction in atherosclerotic cardiovascular diseases and beyond: from mechanism to pharmacotherapies

S Xu, I Ilyas, PJ Little, H Li, D Kamato, X Zheng… - Pharmacological …, 2021 - ASPET
The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Endothelial dysfunction and coronary artery disease: a state of the art review

M Veerasamy, A Bagnall, D Neely, J Allen… - Cardiology in …, 2015 - journals.lww.com
Atherosclerotic coronary artery disease (CAD) is a major cause of morbidity and mortality in
the developed world. Endothelial dysfunction plays an important role in the development of …

Therapeutic targets for endothelial dysfunction in vascular diseases

DTN Huynh, KS Heo - Archives of Pharmacal Research, 2019 - Springer
Vascular endothelial cells are located on the surface of the blood vessels. It has been
recognized as an important barrier to the regulation of vascular homeostasis by regulating …

Targeting endothelial dysfunction and inflammation

L Wang, CK Cheng, M Yi, KO Lui, Y Huang - Journal of molecular and …, 2022 - Elsevier
Vascular endothelium maintains vascular homeostasis through liberating a spectrum of
vasoactive molecules, both protective and harmful regulators of vascular tone, structural …