Identification of bacterial metabolites modulating breast cancer cell proliferation and epithelial-mesenchymal transition

G Ujlaki, T Kovács, A Vida, E Kókai, B Rauch… - Molecules, 2023 - mdpi.com
Breast cancer patients are characterized by the oncobiotic transformation of multiple
microbiome communities, including the gut microbiome. Oncobiotic transformation of the gut …

Microbiome—microbial metabolome—cancer cell interactions in breast cancer—familiar, but unexplored

E Mikó, T Kovács, É Sebő, J Tóth, T Csonka, G Ujlaki… - Cells, 2019 - mdpi.com
Breast cancer is a leading cause of death among women worldwide. Dysbiosis, an aberrant
composition of the microbiome, characterizes breast cancer. In this review we discuss the …

Indolepropionic acid, a metabolite of the microbiome, has cytostatic properties in breast cancer by activating AHR and PXR receptors and inducing oxidative stress

Z Sári, E Mikó, T Kovács, L Jankó, T Csonka, G Lente… - Cancers, 2020 - mdpi.com
Oncobiotic transformation of the gut microbiome may contribute to the risk of breast cancer.
Recent studies have provided evidence that the microbiome secretes cytostatic metabolites …

The interplay between microbiota and chemotherapy-derived metabolites in breast cancer

J Plaza-Diaz, AI Álvarez-Mercado - Metabolites, 2023 - mdpi.com
The most common cancer in women is breast cancer, which is also the second leading
cause of death in this group. It is, however, important to note that some women will develop …

The crosstalk of the human microbiome in breast and colon cancer: a metabolomics analysis

AG Mukherjee, UR Wanjari, P Bradu, R Murali… - Critical Reviews in …, 2022 - Elsevier
The human microbiome's role in colon and breast cancer is described in this review.
Understanding how the human microbiome and metabolomics interact with breast and colon …

Microbial alterations and risk factors of breast cancer: connections and mechanistic insights

S Parida, D Sharma - Cells, 2020 - mdpi.com
Breast cancer-related mortality remains high worldwide, despite tremendous advances in
diagnostics and therapeutics; hence, the quest for better strategies for disease management …

Composition and functional potential of the human mammary microbiota prior to and following breast tumor diagnosis

C Hoskinson, K Zheng, J Gabel, A Kump, R German… - Msystems, 2022 - Am Soc Microbiol
Microbiota studies have reported changes in the microbial composition of the breast upon
cancer development. However, results are inconsistent and limited to the later phases of …

Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation

BM Kirkup, A McKee, KA Makin, J Paveley, S Caim… - BioRxiv, 2019 - biorxiv.org
Background Breast cancer is the second most prevalent cancer worldwide with around 1.7
million new cases diagnosed every year. Whilst prognosis is generally favourable in early …

[HTML][HTML] The power of small changes: Comprehensive analyses of microbial dysbiosis in breast cancer

S Parida, D Sharma - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
Disparate occurrence of breast cancer remains an intriguing question since only a subset of
women with known risk factors develop cancer. Recent studies suggest an active role of …

Elucidating the roles of the mammary and gut microbiomes in breast cancer development

C Hoskinson, RY Jiang, LT Stiemsma - Frontiers in Oncology, 2023 - frontiersin.org
The mammary microbiome is a newly characterized bacterial niche that might offer
biological insight into the development of breast cancer. Together with in-depth analysis of …