The evolution of commercial drug delivery technologies

AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …

The future of drug delivery

J Gao, JM Karp, R Langer, N Joshi - Chemistry of Materials, 2023 - ACS Publications
Drug delivery technologies have been proven to improve treatment outcomes in many ways,
including enhancing therapeutic efficacy, reducing toxicity, increasing patient compliance …

Emerging frontiers in drug delivery

MW Tibbitt, JE Dahlman, R Langer - Journal of the American …, 2016 - ACS Publications
Medicine relies on the use of pharmacologically active agents (drugs) to manage and treat
disease. However, drugs are not inherently effective; the benefit of a drug is directly related …

[引用][C] The next frontier of molecular medicine: delivery of therapeutics

RK Jain - Nature medicine, 1998 - nature.com
Despite exciting progress in the biology underlying a variety of proposed molecular
medicines, an unmet challenge Remains—delivery. This problem, how to better target the …

Advances in drug delivery systems, challenges and future directions

TC Ezike, US Okpala, UL Onoja, CP Nwike, EC Ezeako… - Heliyon, 2023 - cell.com
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

Drug delivery systems-an overview

KK Jain - Drug delivery systems, 2008 - Springer
This is an overview of drug delivery systems (DDS), starting with various routes of drug
administration. Various drug formulations, as well as devices used for drug delivery and …

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

S Mitragotri, PA Burke, R Langer - Nature reviews Drug discovery, 2014 - nature.com
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies
and recombinant proteins, poses substantial challenges owing to their large size and …

[PDF][PDF] Targeting strategies for tissue-specific drug delivery

Z Zhao, A Ukidve, J Kim, S Mitragotri - Cell, 2020 - cell.com
Off-target effects of systemically administered drugs have been a major hurdle in designing
therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to …

An overview of drug delivery systems

KK Jain - Drug Delivery Systems, 2020 - Springer
This is an overview of the current drug delivery systems (DDSs) starting with various routes
of drug administration. Various drug formulations are then described as well as devices …

Harnessing the therapeutic potential of biomacromolecules through intracellular delivery of nucleic acids, peptides, and proteins

Y Tian, MV Tirrell, JL LaBelle - Advanced healthcare materials, 2022 - Wiley Online Library
Biomacromolecules have long been at the leading edge of academic and pharmaceutical
drug development and clinical translation. With the clinical advances of new therapeutics …