Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains: DETERGENT-FREE PURIFICATION OF …

KS Song, S Li, T Okamoto, LA Quilliam… - Journal of Biological …, 1996 - ASBMB
Caveolae are plasma membrane specializations that have been implicated in signal
transduction. Caveolin, a 21-24-kDa integral membrane protein, is a principal structural …

Evidence for a regulated interaction between heterotrimeric G proteins and caveolin

S Li, T Okamoto, M Chun, M Sargiacomo… - Journal of Biological …, 1995 - ASBMB
Caveolae are flask-shaped plasma membrane specializations. A 22-kDa protein, caveolin,
is a principal component of caveolar membranes in vivo. As recent evidence suggests that …

Identification of peptide and protein ligands for the caveolin-scaffolding domain: implications for the interaction of caveolin with caveolae-associated proteins

J Couet, S Li, T Okamoto, T Ikezu, MP Lisanti - Journal of Biological …, 1997 - ASBMB
Caveolin, a 21-24-kDa integral membrane protein, is a principal component of caveolae
membranes. We have suggested that caveolin functions as a scaffolding protein to organize …

Expression and Characterization of Recombinant Caveolin: PURIFICATION BY POLYHISTIDINE TAGGING AND CHOLESTEROL-DEPENDENT INCORPORATION …

S Li, KS Song, MP Lisanti - Journal of Biological Chemistry, 1996 - ASBMB
Caveolin, a 22-24-kDa integral membrane protein, is a principal component of caveolar
membranes in vivo. Caveolin has been proposed to function as a scaffolding protein to …

Src tyrosine kinases, Gα subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin: caveolin binding negatively regulates the auto …

S Li, J Couet, MP Lisanti - Journal of Biological Chemistry, 1996 - ASBMB
Caveolae are plasma membrane specializations present in most cell types. Caveolin, a 22-
kDa integral membrane protein, is a principal structural and regulatory component of …

Interaction of a receptor tyrosine kinase, EGF-R, with caveolins: caveolin binding negatively regulates tyrosine and serine/threonine kinase activities

J Couet, M Sargiacomo, MP Lisanti - Journal of Biological Chemistry, 1997 - ASBMB
Caveolin, a 21–24-kDa integral membrane protein, is a principal component of caveolae
membranes. We and others have suggested that caveolin functions as a scaffolding protein …

Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin.

M Chun, UK Liyanage, MP Lisanti… - Proceedings of the …, 1994 - National Acad Sciences
Caveolae are small invaginations of the plasma membrane 50-100 nm in diameter. Since
calcium channels, inositol 1, 4, 5-trisphosphate receptors, and heterotrimeric GTP-binding …

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

MP Lisanti, PE Scherer, ZL Tang, M Sargiacomo - Trends in cell biology, 1994 - Elsevier
Abstract Caveolae, 50–100 nm invaginations that represent a subcompartment of the
plasma membrane, have been known for many years, but their exact roles remain uncertain …

Purification and characterization of smooth muscle cell caveolae.

WJ Chang, YS Ying, KG Rothberg, NM Hooper… - The Journal of cell …, 1994 - rupress.org
Plasmalemmal caveolae are a membrane specialization that mediates transcytosis across
endothelial cells and the uptake of small molecules and ions by both epithelial and …

Caveolins, a family of scaffolding proteins for organizing “preassembled signaling complexes” at the plasma membrane

T Okamoto, A Schlegel, PE Scherer… - Journal of Biological …, 1998 - ASBMB
Caveolae are vesicular invaginations of the plasma membrane. The chief structural proteins
of caveolae are the caveolins. Caveolins form a scaffold onto which many classes of …