[HTML][HTML] Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of Nα-acetyltransferases and point to hNaa10p as the post …
P Van Damme, R Evjenth, H Foyn, K Demeyer… - Molecular & Cellular …, 2011 - ASBMB
The impact of N α-terminal acetylation on protein stability and protein function in general
recently acquired renewed and increasing attention. Although the substrate specificity profile …
recently acquired renewed and increasing attention. Although the substrate specificity profile …
N‐terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N‐terminal acetyltransferases and methionine …
Cotranslational N‐terminal (Nt‐) acetylation of nascent polypeptides is mediated by N‐
terminal acetyltransferases (NATs). The very N‐terminal amino acid sequence largely …
terminal acetyltransferases (NATs). The very N‐terminal amino acid sequence largely …
Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80
N-terminal (Nt) acetylation is a major protein modification catalyzed by N-terminal
acetyltransferases (NATs). Methionine acidic N termini, including actin, are cotranslationally …
acetyltransferases (NATs). Methionine acidic N termini, including actin, are cotranslationally …
[HTML][HTML] NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation
P Van Damme, K Hole, A Pimenta-Marques… - PLoS …, 2011 - journals.plos.org
N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification.
Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher …
Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher …
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
G Liszczak, JM Goldberg, H Foyn… - Nature structural & …, 2013 - nature.com
N-terminal acetylation is ubiquitous among eukaryotic proteins and controls a myriad of
biological processes. Of the N-terminal acetyltransferases (NATs) that facilitate this …
biological processes. Of the N-terminal acetyltransferases (NATs) that facilitate this …
N-terminal acetylation and other functions of Nα-acetyltransferases
J Hollebeke, P Van Damme, K Gevaert - 2012 - degruyter.com
Protein N-terminal acetylation by Nα-acetyltransferases (NATs) is an omnipresent protein
modification that affects a large number of proteins. The exact biological role of N-terminal …
modification that affects a large number of proteins. The exact biological role of N-terminal …
Protein N-terminal acetyltransferases: when the start matters
The majority of eukaryotic proteins are subjected to N-terminal acetylation (Nt-acetylation),
catalysed by N-terminal acetyltransferases (NATs). Recently, the structure of an NAT …
catalysed by N-terminal acetyltransferases (NATs). Recently, the structure of an NAT …
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
T Arnesen, P Van Damme… - Proceedings of the …, 2009 - National Acad Sciences
Nα-terminal acetylation is one of the most common protein modifications in eukaryotes. The
COmbined FRActional DIagonal Chromatography (COFRADIC) proteomics technology that …
COmbined FRActional DIagonal Chromatography (COFRADIC) proteomics technology that …
[HTML][HTML] Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms
OS Rathore, A Faustino, P Prudêncio, P Van Damme… - Scientific reports, 2016 - nature.com
Protein N-terminal acetylation is an ancient and ubiquitous co-translational modification
catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). Prokaryotes …
catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). Prokaryotes …
[HTML][HTML] The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4
K Hole, P Van Damme, M Dalva, H Aksnes… - PloS one, 2011 - journals.plos.org
Protein Nα-terminal acetylation (Nt-acetylation) is considered one of the most common
protein modification in eukaryotes, and 80-90% of all soluble human proteins are modified in …
protein modification in eukaryotes, and 80-90% of all soluble human proteins are modified in …