Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain
disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's …

Schizophrenia is associated with increased levels of oxidative stress, as reflected by an
increase in the concentrations of damaging reactive species and a reduction in anti-oxidant …

Over a century, a wide-ranging variety of pathophysiological models and causal hypotheses
have been conceptualized for schizophrenia. One among these is the role for free radical …

A growing body of evidence has emerged demonstrating a pathological link between
oxidative stress and schizophrenia. This evidence identifies oxidative stress as a …

Oxidative stress has been suggested to contribute to the pathophysiology of schizophrenia.
In particular, oxidative damage to lipids, proteins, and DNA as observed in schizophrenia is …

Background Schizophrenia is a devastating psychiatric disorder with a broad range of
behavioural and biologic manifestations. There are several clinical characteristics of the …

Abnormal redox homeostasis and oxidative stress have been proposed to play a role in the
etiology of several neuropsychiatric spectrum disorders. Emerging interest has recently …

The endogenous production of highly reactive oxidation species is an inherent by-product of
cellular energy metabolism. Cellular antioxidant defense systems (AODS) comprising …

Because increasing evidence point to the convergence of environmental and genetic risk
factors to drive redox dysregulation in schizophrenia, we aim to clarify whether the metabolic …

Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …