Clathrin-mediated endocytosis (CME) is the major route through which cells internalise
various substances and recycle membrane components. Via the coordinated action of many …

Endocytosis includes a number of processes by which cells internalize segments of their
plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis …

Background The dynamic actin cytoskeleton plays an important role in clathrin-mediated
endocytosis (CME). However, its exact functions remain uncertain as a result of a lack of …

Tight regulation of the actin cytoskeleton is critical for many cell functions, including various
forms of cellular uptake. Clathrin-mediated endocytosis (CME) is one of the main methods of …

Endocytosis is a fundamental eukaryotic process required for remodelling plasma-
membrane lipids and protein to ensure appropriate membrane composition. Increasing …

Intracellular signals, activated by plasma membrane receptors, are propagated through a
coordinated series of events ultimately leading to the regulation of basic cellular functions …

▪ Abstract Internalization of receptors, lipids, pathogens, and other cargo at the plasma
membrane involves several different pathways and requires coordinated interactions …

Endocytosis, the process whereby the plasma membrane invaginates to form vesicles, is
essential for bringing many substances into the cell and for membrane turnover. The …

Clathrin-mediated endocytosis in mammalian cells is critical for a variety of cellular
processes including nutrient uptake and cell surface receptor down-regulation. Despite the …

Increasing evidence from a variety of cell types has highlighted the importance of the actin
cytoskeleton during endocytosis. No longer is actin viewed as a passive barrier that must be …