Progress towards the clinical use of antimicrobial peptides: challenges and opportunities

P Espinal, E Fusté, JM Sierra… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction To overcome the challenge of multidrug resistance, natural and synthetic
peptides are candidates to become the basis of innovative therapeutics, featuring diverse …

Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens

M Garvey - Infectious Disease Reports, 2023 - mdpi.com
The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low-
and middle-income countries are particularly susceptible to higher fatality rates and the …

Antimicrobial peptides: an overview of a promising class of therapeutics

A Giuliani, G Pirri, S Nicoletto - Open Life Sciences, 2007 - degruyter.com
Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …

The value of antimicrobial peptides in the age of resistance

M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

Antimicrobial peptide mimics for clinical use: does size matter?

J Svenson, N Molchanova, CI Schroeder - Frontiers in Immunology, 2022 - frontiersin.org
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Antimicrobial peptides: an approach to combat resilient infections

D Parai, P Dey, SK Mukherjee - Current Drug Discovery …, 2020 - ingentaconnect.com
Background: It was apparent by the end of 1980s that the success against the threats of
bacterial pathogens on public health was an illusion, with the rapid development of resistant …

Antimicrobial peptides: has their time arrived?

E Sancho-Vaello, K Zeth - Future Microbiology, 2015 - Taylor & Francis
The survival of human beings on planet earth is becoming severely difficult owing to the
threat of deathly microbes including viruses, bacteria and fungi. During the last decades …

A new era of antibiotics: the clinical potential of antimicrobial peptides

K Browne, S Chakraborty, R Chen… - International journal of …, 2020 - mdpi.com
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

An overview of antimicrobial peptides and the latest advances in their development

JM Sierra, E Fusté, F Rabanal, T Vinuesa… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: The recent dramatic increase in the incidence of antimicrobial resistance has
been recognized by organizations such as the United Nations and World Health …

[HTML][HTML] Antimicrobial peptides as therapeutic agents

M Upton, P Cotter, J Tagg - International journal of microbiology, 2012 - ncbi.nlm.nih.gov
In developing this special issue, we sought to raise awareness of the potential of
antimicrobial peptides (AMPs) for clinical use and to highlight recent developments in the …