Reconstituted dry powder formulations of ZnO-adjuvanted ovalbumin induce equivalent antigen specific antibodies but lower T cell responses than ovalbumin …
M Hellfritzsch, D Christensen, C Foged… - International Journal of …, 2023 - Elsevier
Most licensed human vaccines are based on liquid dosage forms but have poor storage
stability and require continuous and expensive cold-chain storage. In contrast, the use of …
stability and require continuous and expensive cold-chain storage. In contrast, the use of …
Zinc oxide nanoparticles provide an adjuvant effect to ovalbumin via a Th2 response in Balb/c mice
Zinc oxide nanoparticles (ZNPs) have been used in dietary supplements and may cause an
immunomodulatory effect. The present study investigated the effect of ZNPs on antigen …
immunomodulatory effect. The present study investigated the effect of ZNPs on antigen …
Hollow ZnO Nanospheres Enhance Anticancer Immunity by Promoting CD4+ and CD8+ T Cell Populations In Vivo
Appropriate adjuvant aiding in generating robust anticancer immunity is crucial for cancer
immunotherapy. Herein, hollow ZnO (HZnO) nanospheres are synthesized by a facile …
immunotherapy. Herein, hollow ZnO (HZnO) nanospheres are synthesized by a facile …
Effect of antigen structure in subunit vaccine nanoparticles on humoral immune responses
J Park, JA Champion - ACS Biomaterials Science & Engineering, 2023 - ACS Publications
Subunit vaccines offer numerous attractive features, including good safety profiles and well-
defined components with highly characterized properties because they do not contain whole …
defined components with highly characterized properties because they do not contain whole …
OVA-bound nanoparticles induce OVA-specific IgG1, IgG2a, and IgG2b responses with low IgE synthesis
N Yanase, H Toyota, K Hata, S Yagyu, T Seki… - Vaccine, 2014 - Elsevier
There is an urgent requirement for a novel vaccine that can stimulate immune responses
without unwanted toxicity, including IgE elevation. We examined whether antigen ovalbumin …
without unwanted toxicity, including IgE elevation. We examined whether antigen ovalbumin …
Colloidal characteristics and formulation of pure protein particulate vaccines
Objectives We recently reported that dense gas processing of the protein ovalbumin (OVA)
resulted in the formation of particles that were insoluble in water and which retained their …
resulted in the formation of particles that were insoluble in water and which retained their …
Mesoporous ZnO nanocapsules for the induction of enhanced antigen-specific immunological responses
The application of nanotechnology in vaccinology has fuelled rapid advancement towards
the design and development of nanovaccines. Nanoparticles have been found to enhance …
the design and development of nanovaccines. Nanoparticles have been found to enhance …
Comparative molecular immunological activity of physiological metal oxide nanoparticle and its anticancer peptide and rna complexes
Currently, there is a great interest in nanoparticle-based vaccine delivery. Recent studies
suggest that nanoparticles when introduced into the biological milieu are not simply passive …
suggest that nanoparticles when introduced into the biological milieu are not simply passive …
Development of a novel vaccine delivery system based on Gantrez nanoparticles
S Gómez, C Gamazo, BS Roman… - … of nanoscience and …, 2006 - ingentaconnect.com
The adjuvant capacity of a novel vaccine vector “Gantrez-nanoparticles”(NP) towards coated
or encapsulated ovalbumin (OVA) was investigated. OVA nanoparticles were prepared by a …
or encapsulated ovalbumin (OVA) was investigated. OVA nanoparticles were prepared by a …
Lignin nanoparticles as a promising vaccine adjuvant and delivery system for ovalbumin
MS Alqahtani, M Kazi, MZ Ahmad, R Syed… - International Journal of …, 2020 - Elsevier
Vaccination is the most effective strategy of preventing and treating infectious diseases and
the most significant issue in the development of potent vaccines is the sufficient …
the most significant issue in the development of potent vaccines is the sufficient …