Thalamo–cortical network pathology in idiopathic generalized epilepsy: insights from MRI-based morphometric correlation analysis

BC Bernhardt, DA Rozen, KJ Worsley, AC Evans… - Neuroimage, 2009 - Elsevier
Epileptic activity underlying idiopathic generalized epilepsy (IGE) is related to abnormal
thalamo–cortical interactions. Our purpose was to map in vivo the organization of the …

Volumetric and shape analysis of thalamus in idiopathic generalized epilepsy

JH Kim, JB Kim, WK Seo, S Suh, SB Koh - Journal of neurology, 2013 - Springer
Previous studies using voxel-based morphometry (VBM) provided emerging evidence of
structural changes of the thalamus in idiopathic generalized epilepsy (IGE). However, the …

Altered thalamocortical functional connectivity in idiopathic generalized epilepsy

JB Kim, S Suh, WK Seo, K Oh, SB Koh, JH Kim - Epilepsia, 2014 - Wiley Online Library
Objective Aberrant thalamocortical network has been hypothesized to play a crucial role in
the fundamental pathogenesis underlying idiopathic generalized epilepsy (IGE). We aimed …

[HTML][HTML] Functional neuroimaging abnormalities in idiopathic generalized epilepsy

ML McGill, O Devinsky, X Wang, BT Quinn, H Pardoe… - NeuroImage: Clinical, 2014 - Elsevier
Magnetic resonance imaging (MRI) techniques have been used to quantitatively assess
focal and network abnormalities. Idiopathic generalized epilepsy (IGE) is characterized by …

[HTML][HTML] Impairments of thalamic nuclei in idiopathic generalized epilepsy revealed by a study combining morphological and functional connectivity MRI

Z Wang, Z Zhang, Q Jiao, W Liao, G Chen, K Sun… - PloS one, 2012 - journals.plos.org
Objective Neuroimaging evidence suggested that the thalamic nuclei may play different
roles in the progress of idiopathic generalized epilepsy (IGE). This study aimed to …

Reduced thalamocortical functional connectivity in temporal lobe epilepsy

X He, GE Doucet, M Sperling, A Sharan, JI Tracy - Epilepsia, 2015 - Wiley Online Library
Objective In temporal lobe epilepsy (TLE), the thalamus is well known for its role in the
propagation and spread of epileptiform activity. However, the integrity of thalamocortical …

Probabilistic mapping of thalamic nuclei and thalamocortical functional connectivity in idiopathic generalised epilepsy

Y Chen, N Fallon, BAK Kreilkamp, C Denby… - Human Brain …, 2021 - Wiley Online Library
It is well established that abnormal thalamocortical systems play an important role in the
generation and maintenance of primary generalised seizures. However, it is currently …

Community-informed connectomics of the thalamocortical system in generalized epilepsy

Z Wang, S Lariviere, Q Xu, R Vos de Wael, SJ Hong… - Neurology, 2019 - AAN Enterprises
Objective To study the intrinsic organization of the thalamocortical circuitry in patients with
generalized epilepsy with tonic-clonic seizures (GTCS) via resting-state fMRI (rs-fMRI) …

Structural–functional coupling changes in temporal lobe epilepsy

S Chiang, JM Stern, J Engel Jr, Z Haneef - Brain research, 2015 - Elsevier
Alterations in both structural connectivity (SC) and functional connectivity (FC) have been
reported in temporal lobe epilepsy (TLE). However, the relationship between FC and SC …

Mapping limbic network organization in temporal lobe epilepsy using morphometric correlations: insights on the relation between mesiotemporal connectivity and …

BC Bernhardt, KJ Worsley, P Besson, L Concha… - Neuroimage, 2008 - Elsevier
Temporal lobe epilepsy (TLE) is considered primarily a limbic disorder. Our purpose was to
map limbic network organization in TLE and to statistically relate it to neocortical atrophy. We …