Serum C1q as a novel biomarker of sarcopenia in older adults

S Watanabe, K Sato, N Hasegawa… - The FASEB …, 2015 - Wiley Online Library
Aging‐induced elevation in C1q secretion activates the Wnt signaling pathway in muscles,
leading to the development of muscle fibrosis. However, the association between serum …

Resistance training prevents muscle fibrosis and atrophy via down‐regulation of C1q‐induced Wnt signaling in senescent mice

N Horii, M Uchida, N Hasegawa, S Fujie… - The FASEB …, 2018 - Wiley Online Library
Increased complement component 1q (C1q) secretion with aging leads to muscle fibrosis
and atrophy whereas resistance training attenuates circulating C1q levels. This study aimed …

Complement component C3 is associated with body composition parameters and sarcopenia in community-dwelling older adults: a cross-sectional study in Japan

M Nakamura, M Imaoka, K Sakai, T Kubo, R Imai… - BMC geriatrics, 2024 - Springer
Background Chronic inflammation is a factor in the pathogenesis of sarcopenia, which is
characterized by low muscle mass and reduced strength. Complement C3 is important in the …

Association of creatinine-to-cystatin C ratio with myosteatosis and physical performance in older adults: the Japan Shimanami Health Promoting Program

Y Tabara, Y Okada, M Ochi, Y Ohyagi… - Journal of the American …, 2021 - Elsevier
Objective Sarcopenia is a risk factor for poor outcomes in older adults. Identification of
plasma markers may facilitate screening of sarcopenia. We previously reported that …

Coenzyme Q10 Status as a Determinant of Muscular Strength in Two Independent Cohorts

A Fischer, S Onur, P Niklowitz, T Menke, M Laudes… - PLoS …, 2016 - journals.plos.org
Aging is associated with sarcopenia, which is a loss of skeletal muscle mass and function.
Coenzyme Q10 (CoQ10) is involved in several important functions that are related to …

Creatinine-to-cystatin C ratio as a marker of skeletal muscle mass in older adults: J-SHIPP study

Y Tabara, K Kohara, Y Okada, Y Ohyagi, M Igase - Clinical Nutrition, 2020 - Elsevier
Background Sarcopenia increases mortality risk in older adults. Loss of skeletal muscle
mass is a cardinal feature of sarcopenia. The creatinine-to-cystatin C ratio (CCR) has been …

Relationship between sarcopenia and the serum creatinine/cystatin C ratio in Japanese rural community‐dwelling older adults

H Kusunoki, S Tsuji, Y Wada, M Fukai… - JCSM Clinical …, 2018 - Wiley Online Library
Aims Sarcopenia, the age‐related decline in skeletal muscle volume and function, is
associated with negative clinical and socioeconomic outcomes in elderly people. Clinical …

노인남성에있어서C-반응성단백질(CRP) 과근력과의관련성

김도경, 박원하 - 대한스포츠의학회지, 2010 - kiss.kstudy.com
Decline in muscle mass and muscle strength characterizes normal aging. As clinical studies
show a relationship between high C-reactive protein (CRP) level and low muscle mass. The …

Serum creatinine and cystatin C-based index can be a screening biomarker for sarcopenia in older population

S Singhal, S Singh, AD Upadhyay, SN Dwivedi… - European geriatric …, 2019 - Springer
Purpose Considering the clinical impact of sarcopenia, it would be interesting to get a rapid
and sensible screening tool. We conducted a cross-sectional study with the motive to use an …

[HTML][HTML] Mechanistic links underlying the impact of C-reactive protein on muscle mass in elderly

B Wåhlin-Larsson, DJ Wilkinson… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mechanisms underlying the relationship between systemic inflammation
and age-related decline in muscle mass are poorly defined. The purpose of this work was to …