[HTML][HTML] Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke

A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …

Mechanistic modelling of Virchows triad to assess thrombogenicity and stroke risk in atrial fibrillation patients

A Qureshi, M Balmus, GYH Lip… - … Heart Journal-Digital …, 2022 - academic.oup.com
Background Atrial fibrillation (AF) is responsible for almost one third of all strokes, with the
left atrial appendage (LAA) being the primary thromboembolic source due to localised …

Modelling virchow's triad to improve stroke risk assessment in atrial fibrillation patients

A Qureshi, M Balmus, SE Williams… - 2022 Computing in …, 2022 - ieeexplore.ieee.org
Atrial fibrillation (AF) is associated with a significantly increased risk of stroke due to the
presence of three pro-thrombotic mechanisms known as Virchow's triad-blood stasis …

Atrial fibrillation and the prothrombotic state: revisiting Virchow's triad in 2020

WY Ding, D Gupta, GYH Lip - Heart, 2020 - heart.bmj.com
Atrial fibrillation (AF) is characterised by an increased risk of pathological thrombus
formation due to a disruption of physiological haemostatic mechanisms that are better …

Stroke in atrial fibrillation and other atrial dysrhythmias

H Ozdemir, D Sagris, GYH Lip… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review Atrial fibrillation (AF) is a major risk factor for systemic embolism
and ischaemic stroke. Furthermore, AF-related strokes are associated with higher mortality …

[HTML][HTML] Mechanisms and prediction of ischemic stroke in atrial fibrillation patients

E Aarnink, M Zabern, L Boersma, M Glikson - Journal of clinical medicine, 2023 - mdpi.com
Atrial fibrillation (AF) is the most common arrhythmia in adults worldwide and represents an
important burden for patients, physicians, and healthcare systems. AF is associated with …

[HTML][HTML] Demonstration of patient-specific simulations to assess left atrial appendage thrombogenesis risk

M García-Villalba, L Rossini, A Gonzalo… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

[HTML][HTML] Research on the Internal flow Field of left atrial appendage and stroke risk Assessment with different blood models

J Yang, Z Bai, C Song, H Ding, M Chen, J Sun, X Liu - Bioengineering, 2023 - mdpi.com
Extant clinical research has underscored that patients suffering from atrial fibrillation (AF)
bear an elevated risk for stroke, predominantly driven by the formation of thrombus in the left …

Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment

MI Pons, J Mill, A Fernandez-Quilez… - Journal of …, 2022 - Wiley Online Library
Background. Atrial fibrillation (AF) is considered the most common human arrhythmia. In
nonvalvular AF, around 99% of thrombi are formed in the left atrial appendage (LAA) …

Fibrosis, atrial fibrillation and stroke: clinical updates and emerging mechanistic models

PM Boyle, JC Del Álamo, N Akoum - Heart, 2021 - heart.bmj.com
The current paradigm of stroke risk assessment and mitigation in patients with atrial
fibrillation (AF) is centred around clinical risk factors which, in the presence of AF, lead to …