Abstract N-acetyltransferase 10 (NAT10) is an N 4‐acetylcytidine (ac4C) writer that catalyzes
RNA acetylation at cytidine N4 position on tRNAs, rRNAs and mRNAs. Recently, NAT10 and …

Epitranscriptomic RNA modifications, including methylation of adenine and cytidine
residues, are now recognized as key regulators of both cellular and viral mRNA function …

The oldest known highly conserved modification of RNA, N4-acetylcytidine, is widely
distributed from archaea to eukaryotes and acts as a posttranscriptional chemical …

The IL-1β and type I interferon-β (IFN-β) molecules are important inflammatory cytokines
elicited by the eukaryotic host as innate immune responses against invading pathogens and …

Arango et al. expand the repertoire of epitranscriptomic modifications by identifying N 4-
acetylcytidine in mRNA catalyzed by the known dual acetyltransferase NAT10. It occurs …

The human acetyltransferase NAT10 has recently been shown to catalyze formation of N4-
acetylcytidine (ac4C), a minor nucleobase known to alter RNA structure and function. In …

The role of N6-methyladenosine (m6A) modifications has increasingly been associated with
a diverse set of roles in modulating viruses and influencing the outcomes of viral infection …

Abstract N 6‐methyladenosine (m6A) is a chemical modification present in multiple RNA
species and is most abundant in mRNAs. Studies on m6A reveal its comprehensive roles in …

Suppressing cellular signal transducers of transcription 2 (STAT2) is a common strategy that
viruses use to establish infections, yet the detailed mechanism remains elusive, owing to a …

IFI16 (gamma-interferon-inducible protein 16), a predominantly nuclear protein involved in
transcriptional regulation, also functions as an innate immune response DNA sensor and …