[HTML][HTML] Cytoprotective effects of delphinidin for human chondrocytes against oxidative stress through activation of autophagy

DY Lee, YJ Park, MG Song, DR Kim, S Zada, DH Kim - Antioxidants, 2020 - mdpi.com
Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of
oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the …

[HTML][HTML] Dendrobine alleviates cellular senescence and osteoarthritis via the ROS/NF-κB axis

H Chen, M Tu, S Liu, Y Wen, L Chen - International Journal of Molecular …, 2023 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and cartilage degradation. Dendrobine (DEN) is reported to inhibit inflammation and …

[HTML][HTML] Plumbagin prevents osteoarthritis in human chondrocytes through Nrf-2 activation

YX Guo, L Liu, DZ Yan, JP Guo - Molecular Medicine …, 2017 - spandidos-publications.com
Osteoarthritis (OA) is an inflammatory disorder dealing with the focal degradation of articular
cartilage. Oxidative stress and inflammation are the major events in OA. The present study …

[HTML][HTML] Cardamonin attenuates inflammation and oxidative stress in interleukin-1β-stimulated osteoarthritis chondrocyte through the Nrf2 pathway

YJ Peng, JW Lu, CH Lee, HS Lee, YH Chu, YJ Ho… - Antioxidants, 2021 - mdpi.com
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the deterioration
of articular cartilage. The progression of OA leads to an increase in inflammatory mediators …

Natural ingredients-derived antioxidants attenuate H2O2-induced oxidative stress and have chondroprotective effects on human osteoarthritic chondrocytes via Keap1 …

J Yang, X Song, Y Feng, N Liu, Z Fu, J Wu, T Li… - Free Radical Biology …, 2020 - Elsevier
Osteoarthritis (OA) is the most common disabling joint disease and its pathological process
is closely related to oxidative stress. Recent studies have shown that antioxidants allicin …

The chondroprotective effect of diosmin on human articular chondrocytes under oxidative stress

YR Chen, KC Yang, DH Lu, WT Wu… - Phytotherapy …, 2019 - Wiley Online Library
Excessive oxidative stress, which can amplify inflammatory responses, is involved in the
pathologic progression of knee osteoarthritis. Diosmin is known to possess a variety of …

Evaluating the protective effects and mechanisms of diallyl disulfide on interlukin‐1β‐induced oxidative stress and mitochondrial apoptotic signaling pathways in …

A Hosseinzadeh, D Jafari, T Kamarul… - Journal of cellular …, 2017 - Wiley Online Library
The protective effects and mechanisms of DADS on IL‐1β‐mediated oxidative stress and
mitochondrial apoptosis were investigated in C28I2 human chondrocytes. The effect of …

Engeletin protects against TNF-α-induced apoptosis and reactive oxygen species generation in chondrocytes and alleviates osteoarthritis in vivo

H Wang, Z Jiang, Z Pang, G Qi, B Hua… - Journal of …, 2021 - Taylor & Francis
Purpose: Osteoarthritis (OA) is a progressive disease characterized by pain and impaired
joint functions. Engeletin is a natural compound with anti-inflammatory and antioxidant …

[HTML][HTML] Chlorogenic acid protects human chondrocyte C28/I2 cells from oxidative stress-induced cell death through activation of autophagy

S Zada, TM Pham, JS Hwang, M Ahmed, TH Lai… - Life Sciences, 2021 - Elsevier
Aims The development of osteoarthritis (OA), the most common form of arthritis, is commonly
associated with oxidative stress. Indeed, the lack of antioxidant responses largely increases …

Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway

Z Gong, Y Wang, L Li, X Li, B Qiu, Y Hu - Food and Chemical Toxicology, 2023 - Elsevier
Osteoarthritis (OA) is a common degenerative joint disease, mainly presented by the
deterioration of articular cartilage. Amounts of data demonstrated this deterioration is …