[HTML][HTML] Complete structure of the chemosensory array core signalling unit in an E. coli minicell strain

A Burt, CK Cassidy, P Ames, M Bacia-Verloop… - Nature …, 2020 - nature.com
Motile bacteria sense chemical gradients with transmembrane receptors organised in
supramolecular signalling arrays. Understanding stimulus detection and transmission at the …

Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells

J Liu, B Hu, DR Morado, S Jani… - Proceedings of the …, 2012 - National Acad Sciences
The chemoreceptors of Escherichia coli localize to the cell poles and form a highly ordered
array in concert with the CheA kinase and the CheW coupling factor. However, a high …

Architecture and signal transduction mechanism of the bacterial chemosensory array: progress, controversies, and challenges

JJ Falke, KN Piasta - Current opinion in structural biology, 2014 - Elsevier
Highlights•A conserved, ultrasensitive, ultrastable chemosensory array guides bacterial
motility.•Three core proteins form the array framework: receptor, His-kinase, and adaptor.• …

[HTML][HTML] Recent structural advances in bacterial chemotaxis signalling

C Riechmann, P Zhang - Current opinion in structural biology, 2023 - Elsevier
Bacterial chemosensory arrays have served as a model system for in-situ structure
determination, clearly cataloguing the improvement of cryo-electron tomography (cryoET) …

Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling

A Briegel, MS Ladinsky, C Oikonomou, CW Jones… - Elife, 2014 - elifesciences.org
Most motile bacteria sense and respond to their environment through a transmembrane
chemoreceptor array whose structure and function have been well-studied, but many …

Diversity of bacterial chemosensory arrays

W Yang, A Briegel - Trends in microbiology, 2020 - cell.com
Chemotaxis is crucial for the survival of bacteria, and the signaling systems associated with
it exhibit a high level of evolutionary conservation. The architecture of the chemosensory …

Bacterial chemoreceptors: high-performance signaling in networked arrays

GL Hazelbauer, JJ Falke, JS Parkinson - Trends in biochemical sciences, 2008 - cell.com
Chemoreceptors are crucial components in the bacterial sensory systems that mediate
chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive dynamic range …

New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography

A Briegel, ML Wong, HL Hodges, CM Oikonomou… - Biochemistry, 2014 - ACS Publications
Bacterial chemoreceptors cluster in highly ordered, cooperative, extended arrays with a
conserved architecture, but the principles that govern array assembly remain unclear. Here …

The mobility of two kinase domains in the Escherichia coli chemoreceptor array varies with signalling state

A Briegel, P Ames, JC Gumbart… - Molecular …, 2013 - Wiley Online Library
Motile bacteria sense their physical and chemical environment through highly cooperative,
ordered arrays of chemoreceptors. These signalling complexes phosphorylate a response …

Activated chemoreceptor arrays remain intact and hexagonally packed

A Briegel, M Beeby, M Thanbichler… - Molecular …, 2011 - Wiley Online Library
Bacterial chemoreceptors cluster into exquisitively sensitive, tunable, highly ordered, polar
arrays. While these arrays serve as paradigms of cell signalling in general, it remains …