Metabolite profiling of pig seminal plasma identifies potential biomarkers for sperm resilience to liquid preservation

Y Mateo-Otero, P Fernández-López… - Frontiers in Cell and …, 2021 - frontiersin.org
Metabolomic approaches allow the study of downstream gene expression events since
metabolites are considered as the products of cell signaling pathways. For this reason, many …

Integrating Metabolomics into Reproduction: Sperm Metabolism and Fertility Enhancement in Pigs

Y Mateo-Otero - Animal Reproduction Science, 2024 - Elsevier
The last decades of research have revealed that many other factors besides gamete
genomes are able to determine the reproductive outcomes. Indeed, paternal factors have …

Seminal plasma metabolomics analysis of differences in liquid preservation ability of boar sperm

C Song, L Chang, B Wang, Z Zhang… - Journal of Animal …, 2023 - academic.oup.com
The preservation of semen is pivotal in animal reproduction to ensure successful fertilization
and genetic improvement of livestock and poultry. However, investigating the underlying …

Sperm physiology and in vitro fertilising ability rely on basal metabolic activity: insights from the pig model

Y Mateo-Otero, F Madrid-Gambin, M Llavanera… - Communications …, 2023 - nature.com
Whether basal metabolic activity in sperm has any influence on their fertilising capacity has
not been explored. Using the pig as a model, the present study investigated the relationship …

Differential metabolites screening in yak (Bos grunniens) seminal plasma after cryopreservation and the evaluation of the effect of galactose on post-thaw sperm …

Y Fan, X Li, J Li, X Xiong, S Yin, W Fu, P Wang, J Liu… - Theriogenology, 2024 - Elsevier
Sperm survival and activity depend on the provision of energy and nutrients from seminal
plasma (SP). This study aimed to investigate the variations of metabolites within SP before …

Metabolomic fingerprinting of pig seminal plasma identifies in vivo fertility biomarkers

Y Mateo-Otero, P Fernández-López… - Journal of animal …, 2021 - Springer
Background Metabolomic approaches, which include the study of low molecular weight
molecules, are an emerging-omics technology useful for identification of biomarkers. In this …

Metabolomes of sperm and seminal plasma associated with bull fertility

E Memili, AA Moura, A Kaya - Animal reproduction science, 2020 - Elsevier
Bull fertility is crucial for efficient, profitable, and sustainable agriculture of cattle. Despite the
fact that the uses of sperm from low fertility bulls cause millions of dollars economic losses …

Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability

MA Torres, AC Pedrosa, FJ Novais… - Biology of …, 2022 - academic.oup.com
Holding at room temperature is the first step in most boar semen cryopreservation protocols.
It is well accepted that a holding time (HT) of 24 h increases sperm cryotolerance. However …

1H Nuclear Magnetic Resonance of Pig Seminal Plasma Reveals Intra-Ejaculate Variation in Metabolites

Y Mateo-Otero, P Fernández-López, S Gil-Caballero… - Biomolecules, 2020 - mdpi.com
In pigs, ejaculate is expelled in fractions, mainly the sperm-rich fraction (SRF) and the post-
SRF (PSRF), which differ in both sperm content and origin. In addition, intra-ejaculate …

Comparison of the metabolite profile of donkey and horse seminal plasma and its relationship with sperm viability and motility

J Catalán, I Yánez-Ortiz, I Martínez-Rodero… - Research in Veterinary …, 2023 - Elsevier
Previous research revealed that several seminal plasma (SP) metabolites are related to
sperm functionality, fertility, and preservation. While it is understood that variations between …