In this study, a laparoscopic imaging device and a light source able to select wavelengths by
bandpass filters were developed to perform multispectral imaging (MSI) using over 1000 nm …

Introduction Defining tumor from non-tumor tissue is one of the major challenges of cancer
surgery. Surgeons depend on visual and tactile clues to select which tissues should be …

Intraoperative imaging has been studied using conventional devices such as near infrared
(NIR) optical probes and gamma probes. However, these devices have limited depth …

Significance Fluorescence-guided surgery (FGS) provides specific real-time visualization of
tumors, but intensity-based measurement of fluorescence is prone to errors. Multispectral …

Minimally Invasive Surgery (MIS) has expanded broadly in the field of abdominal and pelvic
surgery. Laparoscopic and robotic surgery has improved surgeon ergonomics, instrument …

As surgery has become the standard-of-care for cancer, surgeons have been left
underequipped to identify tumors in the operating room, causing many operations to end in …

The second near-infrared wavelength window (NIR-II, 1,000–1,700 nm) enables
fluorescence imaging of tissue with enhanced contrast at depths of millimetres and at …

Complete surgical removal of tumor tissue is essential for postoperative prognosis after
surgery. Intraoperative tumor imaging and visualization are an important step in aiding …

Image-guided surgery can enhance cancer treatment by decreasing, and ideally eliminating,
positive tumor margins and iatrogenic damage to healthy tissue. Current state-of-the-art near …

Abstract Background Near-Infrared (NIR) intraoperative molecular imaging is a new
diagnostic modality utilized during cancer surgery for the identification of tumors, metastases …