Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig

A Fox, C Gentry, S Patel, A Kesingland, S Bevan - Pain, 2003 - journals.lww.com
Anti-epileptic drugs (AEDs) are increasingly used for the treatment of neuropathic pain.
Oxcarbazepine is a recently introduced AED that is effective in treating epilepsy and has an …

[HTML][HTML] Rationale and evidence for the use of oxcarbazepine in neuropathic pain

E Carrazana, I Mikoshiba - Journal of pain and symptom management, 2003 - Elsevier
Oxcarbazepine is a second-generation antiepileptic drug (AED) with proven efficacy in
managing partial epileptic seizures, with or without secondary generalization, in adults and …

The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain

JC Hunter, KR Gogas, LR Hedley, LO Jacobson… - European journal of …, 1997 - Elsevier
The novel anti-epileptic drugs lamotrigine, felbamate and gabapentin were compared in rat
experimental models of acute (tail flick) and chronic pain: the chronic constriction injury and …

Oxcarbazepine in neuropathic pain

W Nasreddine, A Beydoun - Expert opinion on investigational …, 2007 - Taylor & Francis
Neuropathic pain is a frequent condition that can result from a variety of underlying
conditions and is frequently chronic and difficult to treat. A number of drugs are used to treat …

The effects of α2-adrenoceptor agents on anti-hyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of inflammatory pain

SM Vučković, MA Tomić, RM Stepanović-Petrović… - Pain, 2006 - Elsevier
In this study, the effects of yohimbine (α2-adrenoceptor antagonist) and clonidine (α2-
adrenoceptor agonist) on anti-hyperalgesia induced by carbamazepine and oxcarbazepine …

Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF

BK Beyreuther, C Geis, T Stöhr, C Sommer - Neuropharmacology, 2007 - Elsevier
Chronic muscle pain is a problem with high prevalence in clinical practice and its
pharmacological treatment is difficult. There is a lack of animal models which reliably predict …

The anti-hyperalgesic effects of carbamazepine and oxcarbazepine are attenuated by treatment with adenosine receptor antagonists

MA Tomic, SM Vuckovic, RM Stepanovic-Petrovic… - Pain, 2004 - journals.lww.com
The antinociceptive effects of carbamazepine and oxcarbazepine, and the influence of
caffeine, were examined in a paw pressure test in rats. Carbamazepine (10–40 mg/kg; …

The suppressive effects of oxcarbazepine on mechanical and cold allodynia in a rat model of neuropathic pain

Y Jang, ES Kim, SS Park, J Lee… - Anesthesia & Analgesia, 2005 - journals.lww.com
IMPLICATIONS: Oxcarbazepine had a dose-dependent antiallodynic effect in a rat model of
neuropathic pain. These results suggest that oxcarbazepine may provide effective therapy …

Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat

MJ Field, S McCleary, J Hughes, L Singh - Pain, 1999 - Elsevier
A single injection of streptozocin (50 mg/kg, ip) led to the development of static and dynamic
allodynia in the rat. The two responses were detected, respectively, by application of …

A comparison of the glutamate release inhibition and anti‐allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain

TJ Coderre, N Kumar, CD Lefebvre… - Journal of …, 2007 - Wiley Online Library
The effects of treatment with the anti‐convulsant agents, lamotrigine and riluzole were
compared with gabapentin in a rat experimental model of neuropathic pain. Rats were …