Background Flavivirus infections pose a significant global health burden underscoring the
need for the development of safe and effective vaccination strategies. Available flavivirus …

Flaviviruses have an increasing global impact as arthropod-transmitted human pathogens,
exemplified by Zika, dengue, yellow fever (YF), West Nile, Japanese encephalitis, and tick …

Several human-pathogenic flaviviruses (including yellow fever, dengue, Japanese
encephalitis, West Nile and tick-borne encephalitis viruses) have a significant public health …

Most areas of the globe are endemic for at least one flavivirus, putting billions at risk for
infection. This diverse group of viral pathogens causes a range of manifestations in humans …

Appropriate administration of yellow fever (YF) or Japanese encephalitis (JE) vaccines to
travelers requires an assessment of the traveler's risk for infection with these vector-borne …

Background Yellow fever (YF) vaccines are highly effective and have a well-established
safety profile despite the risk of rare serious adverse events (SAEs), vaccine-associated …

Recent outbreaks of yellow fever virus (YFV) in West Africa and Brazil resulted in rapid
depletion of global vaccine emergency stockpiles and raised concerns about being …

Human pathogenic flaviviruses pose a significant health concern and vaccination is the most
effective instrument to control their circulation. How pre-existing immunity to antigenically …

The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …

A randomized, double-blind, study was conducted to evaluate the safety, tolerability and
immunogenicity of a live attenuated Japanese encephalitis chimeric virus vaccine (JE-CV) …