5-fluorouracil (5-FU) is one of the most widely used chemotherapy drugs for malignant
tumors. However, intestinal mucositis caused by 5-FU is a severe dose-limiting toxic effect …

Background: Isoliquiritin belongs to flavanol glycosides and has a strong antiinflammatory
activity. This study sought to investigate the anti-inflammatory effect of isoliquiritin and its …

Background Huai Hua San (HHS), a famous Traditional Chinese Medicine (TCM) formula,
has been widely applied in treating ulcerative colitis (UC). However, the interaction of …

Ulcerative colitis is a chronic and recurrent inflammatory bowel disease mediated by
immune response. Geniposide is the main active ingredient extracted from Gardenia …

Ulcerative colitis (UC) is a chronic, relapsing, and nonspecific inflammatory bowel disease
(IBD). Phillygenin (PHI), a natural bioactive ingredient, isolated from Forsythiae Fructus …

Ulcerative colitis (UC) is a chronic and recurrent autoimmune disease, characterized by
recurrence and remission of mucosal inflammation. Although the understanding of the …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, and Gegen Qinlian
Decoction (GQD), a Chinese botanical formula, has exhibited beneficial efficacy against UC …

Colorectal cancer (CRC) is one of the most common malignancies. Isoliquiritigenin (ISL), a
flavonoid phytoestrogen, has shown anti-tumour activities against various cancers …

Abstract Ethnopharmacological relevance “Huai Hua San”(HHS) is one of the first hundred
ancient classic prescriptions drugs, which is commonly used to treat hemorrhoids, colitis …

Fluorouracil (5-FU)-induced intestinal mucositis (IM) is one of the most common oncological
problem. It involves serious clinical consequences such as diarrhea, erythematous lesions …