Management of Portal Hypertension in Patients with Hepatocellular Carcinoma on Systemic Treatment: Current Evidence and Future Perspectives

V De Gaetano, M Pallozzi, L Cerrito, F Santopaolo… - Cancers, 2024 - mdpi.com
Simple Summary Portal hypertension (PH) and hepatocellular carcinoma (HCC) are major
complications of liver cirrhosis with a detrimental impact on patient outcomes that share …

Treatment of portal hypertension in patients with HCC in the era of Baveno VII

D Thabut, M Kudo - Journal of Hepatology, 2023 - Elsevier
Portal hypertension (PHT) and hepatocellular carcinoma (HCC) often coexist, and their
association impairs the prognosis of patients with cirrhosis. The interplay between these two …

Portal hypertension and hepatocellular carcinoma: Des liaisons dangereuses…

M Allaire, M Rudler, D Thabut - Liver International, 2021 - Wiley Online Library
Abstract Background and Aims Portal hypertension (PHT) and hepatocellular carcinoma
(HCC) are major complication of cirrhosis which significantly contribute to morbidity and …

Portal hypertension and variceal bleeding in patients with liver cancer: evidence gaps for prevention and management

M Allaire, D Thabut - Hepatology, 2024 - journals.lww.com
Results: Recent therapeutic advances observed in the management of HCC, notably
through the advent of immunotherapy, have led to a clear improvement in the survival of …

[HTML][HTML] Portal hypertension and hepatocellular carcinoma: navigating uncharted waters

S Sidali, JC Nault - United European Gastroenterology Journal, 2022 - ncbi.nlm.nih.gov
Portal hypertension (PHT) is the main determinant of liver cirrhosis decompensation, defined
by the occurrence of ascites, variceal bleeding or hepatic encephalopathy. 1, 2 A portal …

Screening and management of portal hypertension in advanced hepatocellular carcinoma: A French practice survey

M Allaire, S Manfredi, L Lerosey… - Clinics and Research in …, 2023 - Elsevier
Background Portal hypertension (PHT) and hepatocellular carcinoma (HCC) are two major
complications of cirrhosis that are closely linked and impact patients prognosis, particularly …

Efficacy and safety of atezolizumab plus bevacizumab in patients with portal hypertension for unresectable hepatocellular carcinoma

T Kinami, S Uchikawa, T Kawaoka… - Cancer …, 2024 - Wiley Online Library
Aim Atezolizumab plus bevacizumab combination therapy (Atezo+ Beva) is used as the first‐
line therapy for unresectable hepatocellular carcinoma (u‐HCC). Serious adverse events …

Portal hypertension is associated with poorer outcome and clinical liver decompensation in patients with HCC treated with Atezolizumab-Bevacizumab

P Sultanik, C Campani, E Larrey, B Campion… - Digestive and Liver …, 2024 - Elsevier
Background Portal hypertension (PHT) often complicates hepatocellular carcinoma (HCC)
treatment and prognosis. We aimed to assess PHT's impact on AtezoBev outcomes and …

Management of portal hypertension in patients treated with atezolizumab and bevacizumab for hepatocellular carcinoma

I Ollivier-Hourmand, M Allaire… - Journal of …, 2022 - journal-of-hepatology.eu
One other concern is primary prophylaxis in case of NSBB contraindication or intolerance. In
patients treated with bevacizumab, EBL is the alternative to NSBBs, but we have to keep in …

Influence of clinically significant portal hypertension on surgical outcomes and survival following hepatectomy for hepatocellular carcinoma: a systematic review and …

SB Choi, HJ Kim, TJ Song, HS Ahn… - Journal of Hepato …, 2014 - Wiley Online Library
Surgical resection is not indicated in patients with portal hypertension in the current
guideline of B arcelona Clinic Liver Cancer (BCLC) stage. We report a systematic review …