Phytoestrogens (resveratrol and equol) for estrogen-deficient skin—controversies/misinformation versus anti-aging in vitro and clinical evidence via nutraceutical …

ED Lephart - International Journal of Molecular Sciences, 2021 - mdpi.com
The overarching theme for this review is perspective. Superfoods (a marketing term for fruits
and vegetables, etc.) have a positive connotation, while many superfoods contain …

Menopause and the skin: old favorites and new innovations in cosmeceuticals for estrogen-deficient skin

ED Lephart, F Naftolin - Dermatology and therapy, 2021 - Springer
Estrogen is a pivotal signaling molecule; its production is regulated by the expression of the
aromatase (CYP19A1) gene from ovarian and peripheral tissue sites, and it is transmitted …

Factors influencing skin aging and the important role of estrogens and selective estrogen receptor modulators (SERMs)

ED Lephart, F Naftolin - Clinical, cosmetic and investigational …, 2022 - Taylor & Francis
The narrative for this overview focuses on updating the factors that influence skin aging and
the important role estrogens and selective estrogen receptor modulators (SERMs) play in …

An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology

F Rispo, G De Negri Atanasio, I Demori… - Frontiers in Cell and …, 2024 - frontiersin.org
Polyphenolic compounds constitute a diverse group of natural components commonly
occurring in various plant species, known for their potential to exert both beneficial and …

Resveratrol, 4′ Acetoxy Resveratrol, R-equol, Racemic Equol or S-equol as Cosmeceuticals to Improve Dermal Health

ED Lephart - International Journal of Molecular Sciences, 2017 - mdpi.com
Phytochemicals are botanical compounds used in dermatology applications as
cosmeceuticals to improve skin health. Resveratrol and equol are two of the best-known …

Skin aging and oxidative stress: Equol's anti-aging effects via biochemical and molecular mechanisms

ED Lephart - Ageing research reviews, 2016 - Elsevier
Oxygen in biology is essential for life. It comes at a cost during normal cellular function,
where reactive oxygen species (ROS) are generated by oxidative metabolism. Human skin …

Recent advances in the anti‐aging effects of phytoestrogens on collagen, water content, and oxidative stress

T Liu, N Li, Y Yan, Y Liu, K Xiong, Y Liu… - Phytotherapy …, 2020 - Wiley Online Library
Skin undergoes degenerative changes as it ages, which include the loss of elasticity,
reductions in the epidermal thickness and collagen content, elastic fiber degeneration, and …

Estrogens and aging skin

MJ Thornton - Dermato-endocrinology, 2013 - Taylor & Francis
Estrogen deficiency following menopause results in atrophic skin changes and acceleration
of skin aging. Estrogens significantly modulate skin physiology, targeting keratinocytes …

Dermatological bioactivities of resveratrol and nanotechnology strategies to boost its efficacy—An updated review

F Mascarenhas-Melo, ARTS Araújo, M Rodrigues… - Cosmetics, 2023 - mdpi.com
Resveratrol is a polyphenolic phytoalexin, whose main natural sources are red grapes, red
wine, berries, and peanuts. When applied to the skin, resveratrol evidences a good …

The influence of phytoestrogens on different physiological and pathological processes: An overview

JCP Petrine, B Del Bianco‐Borges - Phytotherapy Research, 2021 - Wiley Online Library
Functional foods have nutritional properties and organic functions, which are beneficial to
health. Certain types of functional food components are so‐called phytoestrogens, non …