[HTML][HTML] Plasma p-tau181 level predicts neurodegeneration and progression to Alzheimer's dementia: a longitudinal study

YL Wang, J Chen, ZL Du, H Weng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Plasma-based biomarkers would be potential biomarkers for early diagnosis of
Alzheimer's disease (AD) because they are more available and cost-effective than …

Plasma P‐tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant …

JR Chong, NJ Ashton, TK Karikari… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction There is increasing evidence that phosphorylated tau (P‐tau181) is a specific
biomarker for Alzheimer's disease (AD) pathology, but its potential utility in non‐White …

[HTML][HTML] Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer's disease

SD Chen, YY Huang, XN Shen, Y Guo, L Tan… - Translational …, 2021 - nature.com
To assess plasma phosphorylated tau181 (p-tau181) as a progression biomarker in
Alzheimer's disease (AD), we examined longitudinal plasma p-tau181 of 1184 participants …

[HTML][HTML] Phosphorylated tau 181 serum levels predict Alzheimer's disease in the preclinical stage

W Qin, F Li, L Jia, Q Wang, Y Li, Y Wei, Y Li… - Frontiers in Aging …, 2022 - frontiersin.org
Background There is an urgent need for cost-effective, easy-to-measure biomarkers to
identify subjects who will develop Alzheimer's disease (AD), especially at the pre …

Plasma phosphorylated tau181 predicts cognitive and functional decline

TF Tropea, T Waligorska, SX Xie… - Annals of Clinical …, 2023 - Wiley Online Library
Objective To determine if plasma tau phosphorylated at threonine 181 (p‐tau181)
distinguishes pathology‐confirmed Alzheimer's disease (AD) from normal cognition (NC) …

A novel ultrasensitive assay for plasma p‐tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease

F Gonzalez‐Ortiz, PCL Ferreira… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Detection of Alzheimer's disease (AD) pathophysiology among individuals
with mild cognitive changes and those experiencing subjective cognitive decline (SCD) …

[HTML][HTML] Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer's amyloid, tau and FDG PET status

XN Shen, YY Huang, SD Chen, Y Guo, L Tan… - Translational …, 2021 - nature.com
Abstract Plasma phosphorylated-tau181 (p-tau181) showed the potential for Alzheimer's
diagnosis and prognosis, but its role in detecting cerebral pathologies is unclear. We aimed …

[HTML][HTML] Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging …

A Zettergren, J Lord, NJ Ashton, AL Benedet… - Alzheimer's research & …, 2021 - Springer
Background Recent studies suggest that plasma phosphorylated tau181 (p-tau181) is a
highly specific biomarker for Alzheimer's disease (AD)-related tau pathology. It has great …

Plasma phosphorylated tau 181 predicts amyloid status and conversion to dementia stage dependent on renal function

S Lehmann, S Schraen-Maschke, JS Vidal… - Journal of Neurology …, 2023 - jnnp.bmj.com
Objectives Plasma P-tau181 is an increasingly established diagnostic marker for
Alzheimer's disease (AD). Further validation in prospective cohorts is still needed, as well as …

Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative

TK Karikari, AL Benedet, NJ Ashton… - Molecular …, 2021 - nature.com
Whilst cerebrospinal fluid (CSF) and positron emission tomography (PET) biomarkers for
amyloid-β (Aβ) and tau pathologies are accurate for the diagnosis of Alzheimer's disease …