Nutritional immunity: the impact of metals on lung immune cells and the airway microbiome during chronic respiratory disease
Nutritional immunity is the sequestration of bioavailable trace metals such as iron, zinc and
copper by the host to limit pathogenicity by invading microorganisms. As one of the most …
copper by the host to limit pathogenicity by invading microorganisms. As one of the most …
The impact of metal availability on immune function during infection
AJ Monteith, EP Skaar - Trends in Endocrinology & Metabolism, 2021 - cell.com
Nutrient transition metals are required cofactors for many proteins to perform functions
necessary for life. As such, the concentration of nutrient metals is carefully maintained to …
necessary for life. As such, the concentration of nutrient metals is carefully maintained to …
[HTML][HTML] Immunomodulatory role of nutrients: how can pulmonary dysfunctions improve?
SC Gozzi-Silva, FME Teixeira, AJS Duarte… - Frontiers in …, 2021 - frontiersin.org
Nutrition is an important tool that can be used to modulate the immune response during
infectious diseases. In addition, through diet, important substrates are acquired for the …
infectious diseases. In addition, through diet, important substrates are acquired for the …
Nutritional immunity: the battle for nutrient metals at the host–pathogen interface
CC Murdoch, EP Skaar - Nature Reviews Microbiology, 2022 - nature.com
Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …
[PDF][PDF] The impact of dietary transition metals on host-bacterial interactions
CA Lopez, EP Skaar - Cell host & microbe, 2018 - cell.com
Transition metals are required cofactors for many proteins that are critical for life, and their
concentration within cells is carefully maintained to avoid both deficiency and toxicity. To …
concentration within cells is carefully maintained to avoid both deficiency and toxicity. To …
Effects of metal compounds with distinct physicochemical properties on iron homeostasis and antibacterial activity in the lungs: chromium and vanadium
MD Cohen, M Sisco, C Prophete, K Yoshida… - Inhalation …, 2010 - Taylor & Francis
In situ reactions of metal ions or their compounds are important mechanisms by which
particles alter lung immune responses. The authors hypothesized that major determinants of …
particles alter lung immune responses. The authors hypothesized that major determinants of …
Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner
Background Vitamin D is under scrutiny as a potential regulator of the development of
respiratory diseases characterised by chronic lung inflammation, including asthma and …
respiratory diseases characterised by chronic lung inflammation, including asthma and …
[HTML][HTML] The role of iron metabolism in lung inflammation and injury
J Kim, M Wessling-Resnick - Journal of allergy & therapy, 2012 - ncbi.nlm.nih.gov
Iron is required for many vital functions including oxygen transport and energy metabolism.
Protective mechanisms maintain optimal iron concentration involving dynamic regulation of …
Protective mechanisms maintain optimal iron concentration involving dynamic regulation of …
Vitamin D-mediated effects on airway innate immunity in vitro
EM Stapleton, K Keck, R Windisch, MR Stroik… - PloS one, 2022 - journals.plos.org
Introduction Vitamin D supplementation has been suggested to enhance immunity during
respiratory infection season. We tested the effect of active vitamin D (calcitriol) …
respiratory infection season. We tested the effect of active vitamin D (calcitriol) …
Transition metal homeostasis in Streptococcus pyogenes and Streptococcus pneumoniae
AG Turner, YO Cheryl-lynn, MJ Walker… - Advances in microbial …, 2017 - Elsevier
Trace metals such as Fe, Mn, Zn and Cu are essential for various biological functions
including proper innate immune function. The host immune system has complicated and …
including proper innate immune function. The host immune system has complicated and …