BACKGROUND New therapeutic options are often explored in in vivo studies using animals
like rats. Since rats are small, it is difficult to examine them in a computed tomography (CT) …

INTRODUCTION: Osteoporosis is a major health problem in the elderly population
particularly in postmenopausal women. Various techniques are currently available for …

Background To evaluate the feasibility of a micro-image based finite element model to
determine the efficacy of sequential treatments on the bone quality in a rat osteoporosis …

The ovariectomized (OVX) rat is a well established model for osteoporosis research. The
recent development of in vivo micro-computed tomography (micro-CT) provides new …

Purpose: The aim of this study was to observe the bony change in the OVX rat longitudinally
and to study the alendronate effect. Materials and Methods: Eighteen Sprague-Dewley rats …

Osteoporosis is a major public health problem affecting more than 200 million people
worldwide. The use of different animal models, for the study of its pathophysiology and …

Dear Editor, We appreciate Dr. Lelovas and Dr. Dontas' interest and concerns regarding our
manuscript, titled “A multi-factorial analysis of bone morphology and fracture strength of rat …

The treatment of osteoporotic patients is an increasing problem all over the world.
Osteoporosis development and treatment methods are often researched with micro-CT. The …

This study monitored in vivo the effect on bone microarchitecture of initiating antiresorptive
treatment with zoledronic acid in rats at 2 weeks following ovariectomy, an early phase at …

Osteoporosis is a long term systemic bone disease of developing relevance due to the
change in current demography. If left untreated it even leads to the mortality of a person …