[HTML][HTML] Childhood trauma and brain structure in children and adolescents
The dimensional model of adversity proposes that experiences of threat and deprivation
have distinct neurodevelopmental consequences. We examined these dimensions …
have distinct neurodevelopmental consequences. We examined these dimensions …
Distinct associations of deprivation and threat with alterations in brain structure in early childhood
Objective The dimensional model of adversity and psychopathology hypothesizes
deprivation and threat impact distinct neurobiological pathways, such as brain structure. This …
deprivation and threat impact distinct neurobiological pathways, such as brain structure. This …
Childhood adversity and neural development: A systematic review
KA McLaughlin, D Weissman… - Annual review of …, 2019 - annualreviews.org
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
[HTML][HTML] Long-term neural embedding of childhood adversity in a population-representative birth cohort followed for 5 decades
MZ Gehred, AR Knodt, A Ambler, KJ Bourassa… - Biological …, 2021 - Elsevier
Background Childhood adversity has been previously associated with alterations in brain
structure, but heterogeneous designs, methods, and measures have contributed to mixed …
structure, but heterogeneous designs, methods, and measures have contributed to mixed …
An exploration of dimensions of early adversity and the development of functional brain network connectivity during adolescence: Implications for trajectories of …
Different dimensions of adversity may affect mental health through distinct neurobiological
mechanisms, though current supporting evidence consists largely of cross-sectional …
mechanisms, though current supporting evidence consists largely of cross-sectional …
[HTML][HTML] Characterizing the impact of adversity, abuse, and neglect on adolescent amygdala resting-state functional connectivity
Characterizing typologies of childhood adversity may inform the development of risk profiles
and corresponding interventions aimed at mitigating its lifelong consequences. A …
and corresponding interventions aimed at mitigating its lifelong consequences. A …
Childhood violence exposure and social deprivation are linked to adolescent threat and reward neural function
Background Childhood adversity is, unfortunately, highly prevalent and strongly associated
with later psychopathology. Recent theories posit that two dimensions of early adversity …
with later psychopathology. Recent theories posit that two dimensions of early adversity …
Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents
JL Schäfer, KA McLaughlin, GG Manfro… - Developmental …, 2023 - Wiley Online Library
Exposure to childhood adversity has been consistently associated with poor developmental
outcomes, but it is unclear whether these associations vary across different forms of …
outcomes, but it is unclear whether these associations vary across different forms of …
Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience
A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …
structure and function. Advances in our understanding of the neurodevelopmental …
The dichotomy of threat and deprivation as subtypes of childhood maltreatment: Differential functional connectivity patterns of threat and reward circuits in an adult …
Background Childhood maltreatment is associated with reduced activation of the nucleus
accumbens, a central region in the reward network, and overactivity in the amygdala, a key …
accumbens, a central region in the reward network, and overactivity in the amygdala, a key …