Simple Summary The immune system plays an important role in the skeletal system during
bone repair and regeneration, especially in the oral environment with its constant host …

Severe bone defects that extend beyond a critical size do not heal on their own, increasing
the risk of complications and leading to poor outcomes for patients. Healing is a highly …

Background/purpose Relieving immuno-inflammatory responses is the prerequisite step for
treating periodontitis. The angiogenic small molecule, dimethyloxalylglycine (DMOG), and …

Effective bone tissue engineering is important to overcome the unmet clinical challenges of
periodontal tissue regeneration. Successful bone tissue engineering comprises three key …

Mesenchymal stem cells (MSCs) provide an advantageous alternative therapeutic option for
bone regeneration in comparison to current treatment modalities. However, delivering MSCs …

Kishimoto T, Kaneko T, Ukai T, Yokoyama M, Ayon Haro R, Yoshinaga Y, Yoshimura A,
Hara Y. Peptidoglycan and lipopolysaccharide synergistically enhance bone resorption and …

Abstract The 15-deoxy-Δ12, 14-PG J 2 (15d-PGJ 2) has demonstrated excellent anti-
inflammatory results in different experimental models. It can be used with a polymeric …

Aim To investigate the association between periodontal macrophage polarization states and
the alveolar bone levels, and to assess whether glycosylated nano‐hydroxyapatites …

Bone tissue repair is influenced by the synergistic interaction between acute immune
microenvironment and osteogenesis. In this study will be independently by film dispersion …

The design of orthopedic biomaterials has gradually shifted from “immune-friendly” to
“immunomodulatory,” in which the biomaterials are able to modulate the inflammatory …